Using finite element analysis to determine effects of the motion loading method on facet joint forces after cervical disc degeneration

Cai, Xin-Yi; Sang, Dacheng; Yuchi, Chen-Xi; Cui, Wei; Zhang, Chunqiu; Du, Chengbin; Liu, Baoge

doi:10.1016/j.compbiomed.2019.103519

Cited by 62 publications

(48 citation statements)

References 67 publications

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“…The matrix of fibrous ring was developed with a solid unit, and the collagen fiber uses a truss unit. The collagen fibers of the fibrous ring were only subjected to tensile stress but not pressure; the fibers crossed each other at an angle of about 30° and an average angle of ±29° with the intervertebral disc, and were arranged in the form of eight concentric layers, accounting for 16% of the fibrous rings [ 14 ] (Fig. 2 ).…”

Section: Methodsmentioning

confidence: 99%

Analysis and improvement of the three-column spinal theory

et al. 2020

BMC Musculoskelet Disord

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Background Denis and Ferguson et al.’s three-column spinal theory has been widely accepted and applied. However, this three-column theory was proposed based solely on observation and experience without thorough documented data and analysis. The aim of this study was to analyze and improve Denis and Ferguson et al.’s three-column spinal theory to propose a novel three-column concept in epidemiology, morphology and biomechanics. Methods A retrospective analysis of the computed tomography imaging data of patients with a diagnosis of T11-L5 vertebral fractures was conducted between February 2010 and December 2018. Three-dimensional (3D) distribution maps of fracture lines of all subjects were obtained based on 3D mapping techniques. In addition, a 25-year-old health male volunteer was recruited for the vertebral finite element force analysis. Results The present study enrolled 459 patients (age: 48 ± 11.42 years), containing a total of 521 fractured vertebrae. The fracture lines peaked in the upper and the outer third sections of the vertebra, starting from the anterior part of the vertebral pedicles in 3-D maps. Regarding flexion and extension of the spine, the last third of the vertebral body in front of the spinal canal was one main stress center in the finite element analysis. The stress on the vertebral body was greater in front of the pedicles in the lateral bending. Conclusion The study reveals that the posterior one-third of the vertebral body in front of the spinal canal and the posterior one-third of the vertebral body in front of the pedicle are very different in terms of fracture characteristics and risks to spinal canal (3D maps and stress distributing graphs), therefore, they should be classified as different columns. We provide strong evidence that Su’s three-column theory complies with the characteristics of vertebral physiological structure, vertebral fracture, and vertebral biomechanics. Graphical abstract

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Section: Methodsmentioning

confidence: 99%

Analysis and improvement of the three-column spinal theory

et al. 2020

BMC Musculoskelet Disord

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“…The material properties and element types of each component of cervical spine model (C3-C7) are shown in Table 1. Loading and boundary conditions each level through these connector units [23,38]. During the whole loading process, the inferior surface of the C7 endplate was always fixed in six directions.…”

Section: Development Of Modelmentioning

confidence: 99%

“…Much of the previous researches of pressure into discs of have focused on the lumbar spine and these studies have shown that nucleus pressure increase with the increase of compressive loads and are related to the grade of intervertebral disc degeneration [11,[23][24]. The studies of examining the influence of the follower load on the nucleus pressure in the thoracic spine are also more and more attractive to the researchers [25][26].…”

Section: Introductionmentioning

confidence: 99%

Finite element study on effect of follower load on intersegmental rotation, facet joint force and nucleus pressure of the cervical spine

Cai¹,

Yuchi²,

Du³

et al. 2019

Preprint

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Background: The follower load is used to simulate the physiological compressive load of human spine. These compressive loads can maintain cervical spine’s mechanics stability and play a significant role in improving load-carrying capacity of the cervical spine. However, under different follower loads the biomechanical response of the cervical spine is unknown. So the aim of this study is to investigate the effect of follower load on biomechanics of the cervical spine. Results: In this study, a three-dimensional nonlinear finite element (FE) model of the cervical spine (C3-C7) was built and validated. Using this FE model of the cervical spine, we evaluated the effect of different follower loads on intersegmental rotation, facet joint force, and nucleus pressure in the cervical spine. The results indicated that with the follower load increased, the intersegmental rotation of the cervical spine in extension decreased, but the intersegmental rotation in other postures increased. The follower load increased the facet joint forces in all postures. In lateral bending (LB), the facet joint forces were only generated in the ipsilateral facet joints. In axial rotation (AR), there was a large asymmetry in the facet joint forces, and this asymmetry worsened with the follower load increased. The nucleus pressure of each segment nonlinearly increased with the follower load increased in all postures. Conclusion: An comprehensive analysis in intersegmental rotation, facet joint force and nucleus pressure under different follower loads can provide us a deeper understanding of the follower load in the human spine.

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“…In spine surgery, computer-assisted techniques have been increasingly used in various stages of surgical planning and/or execution, e.g., to determine the optimal trajectory for the insertion of pedicle screws (Goerres et al, 2017;Knez et al, 2019;Mischler et al, 2020), but also to improve surgical navigation and allow an improved execution of the surgical plan (Liebmann et al, 2020;Müller et al, 2020). Biomechanical models can provide information on the preoperative pathological condition such as degenerative changes and their biomechanical consequences (Du et al, 2016;Cai et al, 2020). Patient-specific simulations can be used to analyze the effects of different surgical procedures on specific structures and pathologies.…”

Section: Introductionmentioning

confidence: 99%

Automated Pipeline to Generate Anatomically Accurate Patient-Specific Biomechanical Models of Healthy and Pathological FSUs

Caprara

Carrillo

Snedeker

et al. 2021

Front. Bioeng. Biotechnol.

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State-of-the-art preoperative biomechanical analysis for the planning of spinal surgery not only requires the generation of three-dimensional patient-specific models but also the accurate biomechanical representation of vertebral joints. The benefits offered by computational models suitable for such purposes are still outweighed by the time and effort required for their generation, thus compromising their applicability in a clinical environment. In this work, we aim to ease the integration of computerized methods into patient-specific planning of spinal surgery. We present the first pipeline combining deep learning and finite element methods that allows a completely automated model generation of functional spine units (FSUs) of the lumbar spine for patient-specific FE simulations (FEBio). The pipeline consists of three steps: (a) multiclass segmentation of cropped 3D CT images containing lumbar vertebrae using the DenseVNet network, (b) automatic landmark-based mesh fitting of statistical shape models onto 3D semantic segmented meshes of the vertebral models, and (c) automatic generation of patient-specific FE models of lumbar segments for the simulation of flexion-extension, lateral bending, and axial rotation movements. The automatic segmentation of FSUs was evaluated against the gold standard (manual segmentation) using 10-fold cross-validation. The obtained Dice coefficient was 93.7% on average, with a mean surface distance of 0.88 mm and a mean Hausdorff distance of 11.16 mm (N = 150). Automatic generation of finite element models to simulate the range of motion (ROM) was successfully performed for five healthy and five pathological FSUs. The results of the simulations were evaluated against the literature and showed comparable ROMs in both healthy and pathological cases, including the alteration of ROM typically observed in severely degenerated FSUs. The major intent of this work is to automate the creation of anatomically accurate patient-specific models by a single pipeline allowing functional modeling of spinal motion in healthy and pathological FSUs. Our approach reduces manual efforts to a minimum and the execution of the entire pipeline including simulations takes approximately 2 h. The automation, time-efficiency and robustness level of the pipeline represents a first step toward its clinical integration.

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Using finite element analysis to determine effects of the motion loading method on facet joint forces after cervical disc degeneration

Cited by 62 publications

References 67 publications

Analysis and improvement of the three-column spinal theory

Analysis and improvement of the three-column spinal theory

Finite element study on effect of follower load on intersegmental rotation, facet joint force and nucleus pressure of the cervical spine

Automated Pipeline to Generate Anatomically Accurate Patient-Specific Biomechanical Models of Healthy and Pathological FSUs

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