2021
DOI: 10.1101/2021.12.12.21267687
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Using genetic data to identify transmission risk factors: statistical assessment and application to tuberculosis transmission

Abstract: Identifying host factors that influence infectious disease transmission is an important step toward developing interventions to reduce disease incidence. Recent advances in methods for reconstructing infectious disease transmission events using pathogen genomic and epidemiological data open the door for investigation of host factors that affect onward transmission. While most transmission reconstruction methods are designed to work with densely sampled outbreaks, these methods are making their way into surveil… Show more

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