Internet of Things and Cyber-Physical Systems are paradigms that have an important influence on enterprise systems architecture and implementation. The Cognitive Manufacturing as well as the Cognitive Enterprise are emerging models, related to these paradigms, that intend to redesign in the Enterprise Information Model by integrating new information processing and problem-solving methods. This paper intends to analyses and discuss Cognitive Enterprise enablers and principles considering an approach based on models of human brain perception-reasoning-learning processes.