Using helical CT to evaluate renal cell carcinoma in patients undergoing hemodialysis: value of early enhanced images.

Takebayashi, Shigeo; Hatta, Hideo; Chiba, Tetsuo; Takagi, Hidenobu; Koike, Shinji; Matsubara, Sho

doi:10.2214/ajr.172.2.9930797

Cited by 36 publications

(16 citation statements)

References 4 publications

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“…Among them, early CECT and DWI have shown promising results. Takebayashi et al [4] demonstrated that early enhanced helical CT was able to detect more RCCs than delayed enhanced helical CT in ESRD patients with and without acquired cystic kidney disease because the cortex of the ESRD kidneys shows minimal enhancement in the early phase, rendering higher differences in the attenuation values between the RCC and the atrophic parenchyma. However, as ESRD patients require life-long follow-up, screening with CECT may be burdensome in that it uses ionizing radiation and poses a risk for contrast-induced nephropathy.…”

Section: Discussionmentioning

confidence: 99%

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Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease

et al. 2014

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Purpose:The aim of this study was to explore the usefulness of the resistive index (RI) on spectral Doppler ultrasonography (US) in the detection of renal cell carcinoma (RCC) in patients with end-stage renal disease (ESRD).Methods:Seventeen ESRD patients with kidneys in which renal masses were suspected in routine US were subjected. They underwent computed tomography scans and additional Doppler US for the characterization of the detected lesions. All underwent radical nephrectomy with the suspicion of RCC. Fourteen patients finally were included. RI measurements were conducted in the region of the suspected renal mass and the background renal parenchyma. The intraclass correlation coefficient was used to assess the reproducibility of the RI measurement. A paired t-test was used to compare the RI values between the renal mass and the background renal parenchyma (P<0.05).Results:The RI values measured at the RCCs were significantly lower than those measured at the background renal parenchyma (0.41-0.65 vs. 0.75-0.89; P<0.001). The intrareader reproducibility proved to be excellent and good for the renal masses and the parenchyma, respectively (P<0.001).Conclusion:RI on spectral Doppler US is useful in detecting RCC in patients with ESRD. The RI values measured at the RCCs were significantly lower than those measured at the background renal parenchyma.

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Section: Discussionmentioning

confidence: 99%

“…Previously, investigators have assessed the value of CECT and diffusion-weighted image (DWI) for detecting RCC in ESRD kidneys [4,5]. Despite the excellent results, there are some concerns regarding the use of CECT because iodinated contrast agents have the risk of contrast-induced nephropathy.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of resistive index on spectral Doppler ultrasonography in the detection of renal cell carcinoma in patients with end-stage renal disease

et al. 2014

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“…4) [20,21]. It is typically performed both before and after contrast media using 5-mm-thick sections, but studies are more diagnostic when performed as a bolus with early scanning as opposed to scanning after a delay.…”

Section: Imagingmentioning

confidence: 99%

Acquired cystic kidney disease

Choyke

2000

European Radiology

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Acquired cystic kidney disease (ACKD), also known as acquired renal cystic disease (ARCD,) occurs in patients who are on dialysis for end-stage renal disease. It is generally accepted that ACKD develops as a consequence of sustained uremia and can first manifest even before dialysis is initiated while the patient is still in chronic renal failure. The role of immune suppression, particularly in transplant recipients, in the development of ACKD, is still under investigation. The prevalence of ACKD is directly related to the duration of dialysis and the risk of cancer is directly related to the presence of cysts. Herein we review the current understanding of the pathophysiology and imaging implications of ACKD.

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“…Patients on dialysis who have acquired cystic disease have an increased incidence of renal cell cancer. Interestingly, a recent study evaluating the use of CT in patients on haemodialysis found that the CMP of enhancement was more sensitive and specific (96% and 95%, respectively) than delayed images (83% and 94%) for detecting tumours in such patients [24].…”

Section: Characterizing Renal Massesmentioning

confidence: 99%