“…Stacked ensembles have proven to generally be more accurate prediction models than any one base learner alone in clinical contexts [12] , [13] , [14] . In particular, a large number of studies have used stacked ensembles to study COVID-19 data, with many of them focusing on mortality (e.g., [15] , [16] , [17] , [18] , [19] , [20] , [21] ) and a few assessing cardiac events [22] , [23] . In spite of this progress, it remains unclear how to define the best model combinations for strong performance when using stacked generalization.…”