2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing 2009
DOI: 10.1109/ijcbs.2009.77
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Using Mutual Information and Models of Evolution for Improved Pattern Detection

Abstract: Many uses of Information Theory have recently been discovered in the field of bioinformatics -clustering and classification of data, sequence alignment scoring, discovering dependencies between sites in amino acid alignments, etc. Mutual Information has proven itself to be a very convenient metric for determining the dependency between two sets of data, and has advantages over other common statistical methods such as correlation. Models of evolution, or substitution matrices, have always been at the very heart… Show more

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