Using national data to describe characteristics and determine acceptance factors of pharmacists’ interventions: a six-year longitudinal study

Bouzeid, Mayssam; Clarenne, Justine; Pluchart, Hélène; Chanoine, Sébastien; Vermorel, Céline; Bourdelin, Magalie; Charpiat, B.; Conort, O.; Gravoulet, Julien; Janoly‐Dumenil, Audrey; Juste, M.; Mongaret, Céline; Bosson, Jean‐Luc; Bedouch, Pierrick

doi:10.1007/s11096-022-01526-0

Cited by 7 publications

(2 citation statements)

References 34 publications

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“…The repartition of DRPs herein was similar to that reported in the literature 7 25–27. However, some DRPs may be left undetected for non-targeted patients (untreated indication, drug without indication, drug monitoring, and ADE).…”

Section: Discussionsupporting

confidence: 81%

Increasing the number of pharmacist-led medication order reviews using the available workforce: a retrospective study

Reallon,

Yailian,

Paillet

et al. 2023

Eur J Hosp Pharm

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BackgroundDue to staffing constraints, several hospitals have defined targeting strategies for pharmacist-led medication order review, leaving non-targeted patients exposed to potential harmful drug-related problems (DRPs). Using targeting criteria to stratify medication order review level (level 1 (L1): orders, basic patient characteristics; level 2 (L2) or comprehensive medication order review: orders, patient characteristics, medical records, laboratory results) could make it possible to save time and increase the overall number of medication order reviews. This study aims to define targeting criteria to stratify medication order review level and estimate the time saved for the performance of additional medication order reviews.MethodThis retrospective single-centre study included all medication order reviews performed in 2020; DRPs were collected to assess the medication order review level required to detect them. Logistic regressions were performed to define patient characteristics associated with L2. These targeting criteria were applied to the cohort to estimate the time saved and the number of additional medication order reviews which could have been performed using this approach.Results2478 DRPs were reported; 54.2% (1343/2748) could have been detected using an L1 medication order review (representing 48.2% of the patients (829/1721)). L2 medication order reviews were significantly associated with age ≥65 years, male, and renal clearance <60 mL/min (OR≥75yo=1.79; OR65–74yo=1.74; ORfemale=0.74; OR30–59mL/min=1.67; OR<30mL/min=2.62; p<0.05). Sex being a confounding factor, only age and renal clearance were used as targeting criteria. The time saved was estimated at 274 hours per year, leading to an additional 1720 medication order reviews (54 hospital beds).ConclusionThe proposed approach would maintain a satisfying level of safety and quality for patients, by performing an L2 medication order review for targeted patients based on age and renal clearance, while improving medication order review coverage with an L1 medication order review for non-targeted patients, using the available workforce.

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Section: Discussionsupporting

confidence: 81%

Increasing the number of pharmacist-led medication order reviews using the available workforce: a retrospective study

Reallon,

Yailian,

Paillet

et al. 2023

Eur J Hosp Pharm

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“…4.31%) [ 29 ]. In terms of indication, literature data varies between 9.5% and 19.1% for a missing indication and in contrast for an untreated indication from 4.5% to 20.3% [ 24 , 29 , 50 , 51 ]. Due to direct patient interviews, the rate of patient counseling is considerably high in our study.…”

Section: Discussionmentioning

confidence: 99%

Enhancing drug therapy in ostomy patients: Best practice recommendations for medication management

Berger,

Reeh,

Scherer

et al. 2024

PLoS ONE

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Background Ostomy surgery is a common procedure that poses various challenges for patients and healthcare professionals. There are numerous guidelines addressing different ostomy-related problems (ORPs) and supporting an interdisciplinary approach for ostomy care, but evidence-based literature for optimizing drug therapy after ostomy surgery is lacking. Aim To investigate and characterize typical ORPs in relation to drug therapy and provide best practice recommendations from a pharmaceutical point of view. Methods Patients with an ileo- or colostomy were consecutively enrolled in a prospective, interventional monocentric cohort study during hospitalization, with particular attention to medication. A clinical pharmacist assessed DRPs by performing level 3 medication reviews and patient interviews. Pharmacists’ interventions (PIs) were evaluated by two senior clinical pharmacists and documented in DokuPIK (Documentation of Pharmacists’ Interventions in the Hospital). Following interdisciplinary discussions, physicians either accepted or rejected the proposed changes in drug therapy. Comparisons were made between ileostomy and colostomy patients regarding type and extent of PIs. Results Out of the 80 patients included in the cohort, 54 (67.5%) had an ileostomy and 26 (32.5%) a colostomy. In this study, 288 PIs were documented (234 ileostomy vs. 54 colostomy), of wich 94.0% were accepted and implemented by the physicians. The most common reason for PIs in both subgroups (29.6% ileostomy vs. 26.1% colostomy) was a missing drug although indicated (e.g. no loperamide, but high stoma output). The proportion of PIs associated with the ostomy was higher in ileostomy patients (48.3% ileostomy vs. 31.5% colostomy; p = 0.025). Typical ORPs were extracted and analyzed as case studies including recommendations for their respective management and prevention. Conclusion This study highlights the importance of clinical pharmacists being a part of interdisciplinary teams to collaboratively improve ostomy care and patient safety. Especially ileostomy patients are more vulnerable for ORPs in the context of drug therapy and need to be monitored carefully.

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Preliminary guidelines for the detection and management of drug-related problems in cancer patients with type 2 diabetes mellitus: a practical resource for oncology pharmacists

Gossery,

Clarenne,

Barraud

et al. 2024

Support Care Cancer

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Using national data to describe characteristics and determine acceptance factors of pharmacists’ interventions: a six-year longitudinal study

Cited by 7 publications

References 34 publications

Increasing the number of pharmacist-led medication order reviews using the available workforce: a retrospective study

Increasing the number of pharmacist-led medication order reviews using the available workforce: a retrospective study

Enhancing drug therapy in ostomy patients: Best practice recommendations for medication management

Preliminary guidelines for the detection and management of drug-related problems in cancer patients with type 2 diabetes mellitus: a practical resource for oncology pharmacists

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