“…A patient with Holmes' tremor and a history of basilar-tip aneurysm had 2 episodes of delusional jealousy without mania after initiating pramipexole. 61 The manufacturer reports that psychosis occurred in 1 patient with restless legs syndrome (of 889 patients treated in the premarketing trials). 34 Among the mood disorder studies, psychosis was reported in only 2 treated patients (overall rate of 0.8%): 1 with bipolar depression who developed psychotic mania 12 and another with unipolar depression who experienced hallucinations while taking an unusually large dose of 9 mg/day, which resolved with dose reduction.…”