Self-regulated learning (SRL) requires learners’ active participation, i.e., they need to activate cognitive and metacognitive learning strategies. These strategies can be activated and supported by using cognitive and metacognitive prompts. Extensive research concerning the effects of prompts on SRL is necessary to determine connections between these two concepts. Our study investigates the effects of cognitive and metacognitive activities—i.e., prompts—on learning performance during SRL. Therefore, we developed three types of learning environments that use different types of prompts—cognitive or metacognitive prompts—or no prompts. Moreover, we also used a questionnaire to examine prior knowledge and post-knowledge. Pre- and post-tests show that self-confidence in prior knowledge has a significant effect on self-confidence in post-knowledge, cognitive prompts reduce extrinsic motivation, and knowing how to use cognitive learning strategies enables using cognitive prompts more effectively. These results are partially in line with existing research findings on the effects of prompts in SRL.