Using qualitative research methods to improve recruitment to randomized controlled trials: The Quartet study

Salis, Isabel de; Tomlin, Zelda; Toerien, Merran; Donovan, Jenny

doi:10.1258/jhsrp.2008.008028

Cited by 40 publications

(80 citation statements)

References 11 publications

(16 reference statements)

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“…449 Further work focused on using qualitative analysis of recruitment interviews, followed by feedback to recruiting staff in other trials to see if it could be used to improve recruitment. 450 However, difficulties relating to both logistics and acceptability limited effectiveness. de Salis and colleagues 450 found that, because the analysis and feedback process had not been included in the initial study protocol of the trials, they were faced with governance issues which made it very difficult to implement peer review quickly enough to make a difference in trials currently under way.…”

Section: Discussionmentioning

confidence: 99%

“…450 However, difficulties relating to both logistics and acceptability limited effectiveness. de Salis and colleagues 450 found that, because the analysis and feedback process had not been included in the initial study protocol of the trials, they were faced with governance issues which made it very difficult to implement peer review quickly enough to make a difference in trials currently under way. 450 They also found it difficult to get all members of the study team on board and to commit to the process, concluding that it was important to build it into the study protocol at the trial design stage.…”

Section: Discussionmentioning

confidence: 99%

“…de Salis and colleagues 450 found that, because the analysis and feedback process had not been included in the initial study protocol of the trials, they were faced with governance issues which made it very difficult to implement peer review quickly enough to make a difference in trials currently under way. 450 They also found it difficult to get all members of the study team on board and to commit to the process, concluding that it was important to build it into the study protocol at the trial design stage. In addition, reluctance among recruiting nurses to take part in recording recruitment interviews that would be listened to and scrutinised by researchers outside the study team seriously hampered the process.…”

Section: Discussionmentioning

confidence: 99%

“…Sufficient interviews need to be recorded to capture a good variety of interviews and circumstances and of participant interactions and responses. Second, whereas de Salis and colleagues 450 had been hampered by recruiting nurses' reluctance to record recruitment interviews, we circumvented the nurses' apprehension that others might scrutinise and appraise them by confining the peer review to the recruiting nurses. In addition, making the peer review exclusive to the recruiting nurse team enhanced team cohesion by helping to build trust and foster working relationships, benefiting both communication and efficiency.…”

Section: Discussionmentioning

confidence: 99%

“…450 Although training those responsible for recruitment to a RCT is a crucial part of the set-up phase of a trial, it is often not done in a structured way. Our intervention provided a constructive forum to compare and critique ways of conveying the study information and become skilled at clearly articulating the trial design, which is vital to maximising recruitment.…”

Section: Perioperative Pain Management With Local Anaesthetic Infiltrmentioning

confidence: 99%

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Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Blom

Artz

Beswick

et al. 2016

Programme Grants Appl Res

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms PROGRAMME GRANTS FOR APPLIED RESEARCH VOLUME 4 ISSUE 12 AUGUST 2016 ISSN 2050 DOI 10.3310/pgfar04120Improving patients' experience and outcome of total joint replacement: the RESTORE programme Ashley W Blom, Neil Artz, Andrew D Beswick, Amanda Burston, Paul Dieppe, Karen T Elvers, Rachael Gooberman-Hill, Jeremy Horwood, Paul Jepson, Emma Johnson, Erik Lenguerrand, Elsa Marques, Sian Noble, Mark Pyke, Catherine Sackley, Gina Sands, Adrian Sayers, Victoria Wells and Vikki Wylde Improving patients' experience and outcome of total joint replacement: the RESTORE programme ISSN 2050-4330 (Online) This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/).Editorial contact: nihredit@southampton.ac.ukThe full PGfAR archive is freely available to view online at www.journalslibrary.nihr.ac.uk/pgfar. Print-on-demand copies can be purchased from the report pages of the NIHR Journals Library website: www.journalslibrary.nihr.ac.uk Criteria for inclusion in the Programme Grants for Applied Research journalReports are published in Programme Grants for Applied Research (PGfAR) if (1) they have resulted from work for the PGfAR programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors. Programme Grants for Applied Research programmeThe Programme Grants for Applied Research (PGfAR) programme, part of the National Institute for Health Research (NIHR), was set up in 2006 to produce independent research findings that will have practical application for the benefit of patients and the NHS in the relatively near future. The Programme is managed by the NIHR Central Commissioning Facility (CCF) with strategic input from the Programme Director.The programme is a national response mode funding scheme that aims to provide evidence to improve health outcomes in England through promotion of health, prevention of ill health, and optimal disease management (including safety and quality), with particular emphasis on conditions causing significant disease burden.For more information about the PGfAR programme please visit the website: http://www.nihr.ac.uk/funding/programme-grants-forapplied-research.htm This reportThe research reported in this issue of the journal was funded by PGfAR as project number RP-PG-0407-10070. The contractual start date was in December 2008. The final report began editorial review in September 2014 and was accepted for publication in August 2015. As the funder, the PGfAR programme agreed the research questions and study designs in advance with the investigators. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The PGfAR editors and production house have tried to ensure the accurac...

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Perioperative Pain Management With Local Anaesthetic Infiltrmentioning

confidence: 99%

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Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Blom

Artz

Beswick

et al. 2016

Programme Grants Appl Res

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Development‐dependent and ‐independent ubiquitin expression in divisions of the cockroach mushroom body

Brown

Strausfeld

2006

J of Comparative Neurology

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It has been proposed that the alpha and beta divisions of the mushroom bodies support intermediate and long-term memory whereas the gamma lobes support short-term memory. Here we investigate developmentally dependent versus developmentally independent alterations of mushroom body structure with special emphasis on its lobes. We show that in the cockroach mushroom bodies there are two types of plastic remodeling. One is developmental, in which episodic addition of new circuitry to the alpha and beta lobes is accomplished by newly born Kenyon cells. The second is revealed as a persistent alteration of structure within the gamma lobe. In the alpha/beta lobes, newly generated Kenyon cell axons extend glutamate-immunoreactive collaterals across layers of the axons of mature Kenyon cells. At specific times in each developmental episode (instar) these collaterals express ubiquitin, undergo localized degeneration, and are scavenged by glial cells. In contrast, the mature Kenyon cells that comprise the gamma lobe express detectable ubiquitin throughout each developmental episode. This pattern of ubiquitin expression suggests that the gamma lobe circuitry undergoes continuous modification independent of development.

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Clinicians' views on the feasibility of surgical randomized trials in urogynecology: Results of a questionnaire survey

Bakali

Pitchforth

Tincello

et al. 2010

Neurourology and Urodynamics

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This study highlights the difference between collective and individual equipoise and their impact upon surgical trials. Clinicians held strong views preventing them from regarding the study favorably. Difficulty with relinquishing control over choice of procedure appeared central. These findings support the growing evidence in favor of detailed qualitative pilot work for surgical trials. The role of expertise-based randomization deserves further consideration.

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Using qualitative research methods to improve recruitment to randomized controlled trials: The Quartet study

Cited by 40 publications

References 11 publications

Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Improving patients’ experience and outcome of total joint replacement: the RESTORE programme

Development‐dependent and ‐independent ubiquitin expression in divisions of the cockroach mushroom body

Clinicians' views on the feasibility of surgical randomized trials in urogynecology: Results of a questionnaire survey

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