Using real-world data to estimate the changing trends in the prevalence and incidence of type 2 diabetes mellitus in Xiamen of China from 2014 to 2019

He, Weiwei; Xu, Qiushi; Han, Lili; Wu, Ting; Shi, Xiulin; Ye, Lishan; Yao, Guanhua; Li, Xuejun

doi:10.1186/s12902-021-00759-w

Cited by 4 publications

(5 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…He et al used real-world data to estimate the changing tendencies in the prevalence of T2DM in Xiamen City from 2014 to 2019. Interestingly, the overall prevalence among the male and female adults were 4.18% and 5.52% in Xiamen, and T2DM prevalence exhibited an increasing trend with advancing age regardless of gender [ 50 ]. In our work, female participants were younger than males, which could be one possible reason to explain the prevalence of T2DM were not significantly different between genders.…”

Section: Discussionmentioning

confidence: 99%

The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study

et al. 2022

View full text Add to dashboard Cite

Background Hypertension is highly prevalent and associated with the elevated risks of cardiovascular diseases, dementia, and physical disabilities among adults. Although the correlation between bilirubin and hypertension has been reported, the observation in quinquagenarian population is scarce. We aimed to examine bilirubin-hypertension association in Guankou Ageing Cohort Study. Methods Participants ≥ 55 years were recruited and their questionnaires and physical examination data were collected. Kaplan–Meier survival analysis and Cox proportional hazards regression were implemented to assess the hypertension risk. The non-liner dose–response relationships of bilirubin-hypertension were determined by restricted cubic spline (RCS) models. Receiver operating characteristic (ROC) curves and multiple factors analysis (MFA) were performed to evaluate the predictive abilities. Results 1881 eligible participants (male 43.75%, female 56.25%) with the median age of 61.00 (59.00–66.00) were included. The hazard ratio (HR, 95% CI) of serum total bilirubin (STB) and unconjugated bilirubin (UCB) were 1.03 (1.01–1.05) and 1.05 (1.03–1.07), while conjugated bilirubin (CB) showed a weak protective effect with the HR of 0.96 (0.92–0.99), and the associations remained significant in all models. RCS analyses further indicated the similar bidirectional effects of STB and UCB with the cut-off of 12.17 μmol/L and 8.59 μmol/L, while CB exhibited inverse bidirectional dose–response relationship with a cut-off of 3.47 μmol/L. ROC curves and MFA showed baseline STB combined with age, BMI, and waist circumference could well discriminate the low and high of hypertension risk. Conclusions Our findings suggested the higher levels of total and unconjugated bilirubin were hazardous factors of hypertension, while an inverse effect presented when more bilirubin was conjugated.

show abstract

Section: Discussionmentioning

confidence: 99%

The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Particularly for China, which has the highest prevalence of T2D 6 . According to the research data of He W et al 7 ., the prevalence of T2D in Xiamen is significantly increasing, especially among young people. Similarly, Wang Z et al 8 .…”

Section: Introductionmentioning

confidence: 99%

Optimal obesity- and lipid-related indices for predicting type 2 diabetes in middle-aged and elderly Chinese

Zhang,

Wang,

et al. 2024

Sci Rep

View full text Add to dashboard Cite

To investigate the screening and predicting functions of obesity- and lipid-related indices for type 2 diabetes (T2D) in middle-aged and elderly Chinese, as well as the ideal predicted cut-off value. This study's data comes from the 2011 China Health and Retirement Longitudinal Study (CHARLS). A cross-sectional study design was used to investigate the relationship of T2D and 13 obesity- and lipid-related indices, including body mass index (BMI), waist circumference (WC), waist–height ratio (WHtR), visceral adiposity index (VAI), a body shape index (ABSI), body roundness index (BRI), lipid accumulation product (LAP), conicity index (CI), Chinese visceral adiposity index (CVAI), triglyceride- glucose index (TyG index) and its correlation index (TyG-BMI, TyG-WC, TyG-WHtR). The unadjusted and adjusted correlations between 13 indices and T2D were assessed using binary logistic regression analysis. The receiver operating characteristic curve (ROC) was used to determine the usefulness of anthropometric indices for screening for T2D and determining their cut‑off value, sensitivity, specificity, and area under the curve (AUC). The study comprised 9488 people aged 45 years or above in total, of whom 4354 (45.89%) were males and 5134 (54.11%) were females. Among them were 716 male cases of T2D (16.44%) and 870 female cases of T2D (16.95%). A total of 13 obesity- and lipid-related indices were independently associated with T2D risk after adjusted for confounding factors (P < 0.05). According to ROC analysis, the TyG index was the best predictor of T2D among males (AUC = 0.780, 95% CI 0.761, 0.799) and females (AUC = 0.782, 95% CI 0.764, 0.799). The AUC values of the 13 indicators were higher than 0.5, indicating that they have predictive values for T2D in middle-aged and elderly Chinese. The 13 obesity- and lipid-related indices can predict the risk of T2D in middle‑aged and elderly Chinese. Among 13 indicators, the TyG index is the best predictor of T2D in both males and females. TyG-WC, TyG-BMI, TyG-WHtR, LAP, and CVAI all outperformed BMI, WC, and WHtR in predicting T2D.

show abstract

“…Some studies have estimated the prevalence of diabetes and obesity in China; however, there are still some limitations [ 6 , 11 , 12 , 13 , 14 , 15 ]. First, several estimates of the prevalence and population size of diabetes in China are not based on China’s diabetes guidelines and diagnostic criteria.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, the situation in China is estimated to be biased. Second, because some studies did not use nationally representative data, the results can only represent certain regions [ 14 , 15 ]. Most importantly, no studies have estimated the prevalence and population size of people with diabetes combined with abnormal body weight in China.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Numbers of Diabetes Patients with Elevated BMI in China: Evidence from a Nationally Representative Cross-Sectional Study

Wang

Liang

Zhou

et al. 2022

IJERPH

View full text Add to dashboard Cite

Background: China is facing the challenges of the increasing burden of diabetes and obesity; the prevalence and numbers of diabetes patients with obesity or overweight are still unclear. Methods: Nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS) were used to estimate the prevalence of diabetes patients with elevated BMI, the recommendation rate for antidiabetic medication, the blood glucose control rate, and the corresponding population size. Results: The prevalence of diabetes patients with elevated BMI was 9.18% (95% CI: 7.88, 10.68; representing 31.54 million) in China. More than half of people with diabetes had elevated BMI (overweight or obesity). Among the participants who were not taking antidiabetic medication, 26.15% (95% CI: 18.00, 36.36; representing 3.79 million) were recommended for antidiabetic medication by the 2020 CDS guideline. There were 24.62% (95% CI: 16.88, 34.45; representing 3.64 million) patients, representing 11.13 (95% CI: 9.86, 12.41) million people, with diabetes combined with elevated BMI, taking antidiabetic medication, and still above the goal blood glucose. Conclusions: Our results indicate that diabetes combined with elevated BMI has become a major public health problem in China in people over 45 years of age. Moreover, the prevalence and population size of women are higher than those of men, and the prevalence of people over 65 years old is slightly lower than that of elderly people aged 45–65. The recommended rate of antidiabetic medication and the control rate of blood glucose were high, and prevention and treatment strategies for diabetes combined with elevated BMI are needed.

show abstract

Using real-world data to estimate the changing trends in the prevalence and incidence of type 2 diabetes mellitus in Xiamen of China from 2014 to 2019

Cited by 4 publications

References 23 publications

The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study

The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study

Optimal obesity- and lipid-related indices for predicting type 2 diabetes in middle-aged and elderly Chinese

Prevalence and Numbers of Diabetes Patients with Elevated BMI in China: Evidence from a Nationally Representative Cross-Sectional Study

Contact Info

Product

Resources

About