“…First, several studies have examined individual's understanding of the concept of synergistic health risks (the risk attributable to the combination is greater than the sum of the risk attributable to each constituent; e.g., Dawson, Johnson, & Luke, ; French, Gayton, Burton, Thorogood, & Marteau, ; Hampson, Andrews, Lee, Lichtenstein, & Barckley, ). These studies have often found relatively low levels of awareness of the synergistic health risks attributable to less ‘ familiar ’ combinations (e.g., drug–drug combinations such as aspirin and clopidogrel), but relatively high levels of awareness of the synergistic risks associated with more ‘ familiar ’ combinations (e.g., alcohol and driving) (Dawson, Johnson, & Luke, , p. 7; Hampson, Andrews, Barckley, Lee, & Lichtenstein, ). This suggests that certain combinations of factors can become familiar, whether through public awareness campaigns or targeted interventions, as being harmful, and individuals often infer that such combinations elicit synergistic effects.…”