“…Although drug use can increase sensation seeking (Ersche et al, 2010), longitudinal results also indicate a direct path leading from sensation seeking to initiation (Horvath et al, 2004). Adolescent sensation seekers are at increased risk for use of various drugs, including alcohol, tobacco, and marijuana (Martin et al, 2002(Martin et al, , 2004Sargent et al, 2010). Young adult high sensation seekers also are more sensitive to the effects of drugs (self-administration, positive subjective effects) than are low sensation seekers under controlled laboratory conditions (Stoops et al, 2007;Perkins et al, 2008;Fillmore et al, 2009;Kelly et al, 2009), suggesting that this facet is present before problem use.…”