2019
DOI: 10.1109/access.2019.2935763
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Using Sequential Decision Making to Improve Lung Cancer Screening Performance

Abstract: Globally, lung cancer is responsible for nearly one in five cancer deaths. The National Lung Screening Trial (NLST) demonstrated the efficacy of low-dose computed tomography (LDCT) to identify early-stage disease, setting the basis for widespread implementation of lung cancer screening programs. However, the specificity of LDCT lung cancer screening is suboptimal, with a significant false positive rate. Representing this imaging-based screening process as a sequential decision making problem, we combined multi… Show more

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Cited by 37 publications
(27 citation statements)
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“…Lung cancer is cause by the uncontrolled increase of lung cells. [3]. Lung nodes are defects of the spherical and circular opaque lung tissue with a diameter of 30 mm.…”
Section: Introductionmentioning
confidence: 99%
“…Lung cancer is cause by the uncontrolled increase of lung cells. [3]. Lung nodes are defects of the spherical and circular opaque lung tissue with a diameter of 30 mm.…”
Section: Introductionmentioning
confidence: 99%
“…For |Z| finite the latent z t variables then might represent distinct progression "stages" or various classifications of a disease. Discrete separation like this is well established in both clinical guidelines and models for a range of cases including transplantation in patients with CF [8], the diagnosis of Alzheimer's disease [45], and cancer screening [47]. Accordingly we use the Attentive State-Space model of [3] to build an attention-based, customised state-space (CSS) representation of disease progression.…”
Section: Environmentsmentioning
confidence: 99%
“…Though the technique improves the accuracy, the huge amounts of data points were not considered. A Markov decision process was developed in [8] to concurrently optimize lung cancer recognition with higher specificity. However, the higher classification performance in detecting malignant pulmonary nodules was not obtained.…”
Section: Introductionmentioning
confidence: 99%