Using Sol-Gel Chemistry to Synthesize a Material with Properties Suited for Chemical Sensing. Development and Implementation of a Materials Science Experiment for the Undergraduate Curriculum

Laughlin, James B.; Sarquis, Jerry L.; Jones, Veronica; Cox, James A.

doi:10.1021/ed077p77

Cited by 21 publications

(12 citation statements)

References 14 publications

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“…An iron leaching experiment, similar to that described by Laughlin et al [24], was replicated three times to determine the relative porosity of the three sol-gel formulas. Three separate batches of sol-gel glass pellets (A,B,C) were prepared as described above, with the following exception: 50 μl of 20 mM ferrous sulfate was added to each instead of 40 μl of purified pyoverdin.…”

Section: Methodsmentioning

confidence: 99%

Iron specificity of a biosensor based on fluorescent pyoverdin immobilized in sol-gel glass

Yoder

Kisaalita

2011

J Biol Eng

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Two current technologies used in biosensor development are very promising: 1. The sol-gel process of making microporous glass at room temperature, and 2. Using a fluorescent compound that undergoes fluorescence quenching in response to a specific analyte. These technologies have been combined to produce an iron biosensor. To optimize the iron (II or III) specificity of an iron biosensor, pyoverdin (a fluorescent siderophore produced by Pseudomonas spp.) was immobilized in 3 formulations of porous sol-gel glass. The formulations, A, B, and C, varied in the amount of water added, resulting in respective R values (molar ratio of water:silicon) of 5.6, 8.2, and 10.8. Pyoverdin-doped sol-gel pellets were placed in a flow cell in a fluorometer and the fluorescence quenching was measured as pellets were exposed to 0.28 - 0.56 mM iron (II or III). After 10 minutes of exposure to iron, ferrous ion caused a small fluorescence quenching (89 - 97% of the initial fluorescence, over the range of iron tested) while ferric ion caused much greater quenching (65 - 88%). The most specific and linear response was observed for pyoverdin immobilized in sol-gel C. In contrast, a solution of pyoverdin (3.0 μM) exposed to iron (II or III) for 10 minutes showed an increase in fluorescence (101 - 114%) at low ferrous concentrations (0.45 - 2.18 μM) while exposure to all ferric ion concentrations (0.45 - 3.03 μM) caused quenching. In summary, the iron specificity of pyoverdin was improved by immobilizing it in sol-gel glass C.

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Section: Methodsmentioning

confidence: 99%

Iron specificity of a biosensor based on fluorescent pyoverdin immobilized in sol-gel glass

Yoder

Kisaalita

2011

J Biol Eng

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“…We show here that sol–gel entrapment2 solves this problem, and makes it possible to place in one‐pot acids and bases without their mutual destruction, while still allowing these reagents to activate or participate in desired reactions. In numerous studies it has been shown that molecules entrapped within sol–gel matrices retain their chemical and physical properties3 and that external substrate molecules can enter the pore network, react with the dopant, and emerge from the pores as products. Thus, the only possible reactivity for the dopant is with diffusable substrates.…”

Section: Methodsmentioning

confidence: 99%

Acids and Bases in One Pot while Avoiding Their Mutual Destruction We gratefully acknowledge support from the Israel Science Foundation (grant 96-98-2) and from the Infrastructure (Tashtiot) Project of the Israel Ministry for Science, Arts and Sports; and from the German–Israeli Foundation for Scientific Research and Development (Grant No. I-530.045.05/97).

Gelman

Blum²,

Avnir³

2001

Angew. Chem. Int. Ed.

136

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“…The gelation proceeds through stages by which the product's rigidity is increased. The final material produced in a room temperature synthesis is a porous glasslike solid, which is termed a xerogel [70]. This xerogel is the sol-gel component of the coating being produced and tested for foundry application.…”

Section: Cos Cosmentioning

confidence: 99%

Foundry Coating Technology: A Review

Nwaogu¹,

Tiedje²

2011

MSA

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The importance of foundry coating in improving the surface quality of castings cannot be over emphasized. The application of mould and core washes creates a high thermal integrity barrier between the metal and the mould resulting in the reduction of the thermal shock experienced by the sand system. These thermal shock leads to series of surface defects such as veining/finning, metal penetration, burn-on/in, scab, rat tail, erosion etc. The use of coatings reduces the tendency of occurrence of these defects. However, the understanding of the coating, its components, characteristics and mechanism of action is important. In this review, a detailed description of these topics and examples are provided where necessary. A potential area of research in foundry coating development, using sol-gel process is suggested. The application of sol-gel technology in the development of foundry coatings is a novel approach

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Using Sol-Gel Chemistry to Synthesize a Material with Properties Suited for Chemical Sensing. Development and Implementation of a Materials Science Experiment for the Undergraduate Curriculum

Cited by 21 publications

References 14 publications

Iron specificity of a biosensor based on fluorescent pyoverdin immobilized in sol-gel glass

Iron specificity of a biosensor based on fluorescent pyoverdin immobilized in sol-gel glass

Foundry Coating Technology: A Review

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