“…When first introduced, the tiling approach was used in conjunction with the one-way analysis of variance (ANOVA) statistical model, wherein the Fisher ratio (F-ratio) of the tiles was calculated and the tiles were ranked in descending F-ratio order. The efficiency of the tile-based F-ratio approach (FRA) was thoroughly investigated across various fields of application, and significant efforts were dedicated to increasing its robustness and enhancing its capabilities. − Additionally, there now exist commercial software that was developed based on the tile-based FRA methodology, making the method more accessible to a broader audience. − Nonetheless, several research studies have proposed some alterations to the aforementioned method to expand its scope to better suit specific practical settings. In this respect, multiple F-ratio amended calculations were suggested, such as the control-normalized F-ratio ( CN FRA) and the minimum variance optimized F-ratio ( MVO FRA).…”