Using the Johns Hopkins Aggregated Diagnosis Groups (ADGs) to Predict Mortality in a General Adult Population Cohort in Ontario, Canada

Austin, Peter C.; Walraven, Carl van; Wodchis, Walter P.; Newman, Alice; Anderson, Geoffrey M.

doi:10.1097/mlr.0b013e318215d5e2

Cited by 321 publications

(273 citation statements)

References 17 publications

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“…These variables included age, income quintile, rural residence, prior breast screening, index mammogram result, breast cancer family history, primary care physician (PCP) visits, the number of Johns Hopkins major aggregate diagnosis groups (ADGs),21 duration of residence in Canada, immigration class and application type, as well as Canadian language proficiency and education level at the time of landing. The full definitions of these variables can be found in Table 2.…”

Section: Methodsmentioning

confidence: 99%

Breast screening participation and retention among immigrants and nonimmigrants in British Columbia: A population‐based study

et al. 2018

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Breast cancer screening programs operate across Canada providing mammography to women in target age groups with the goal of reducing breast cancer mortality through early detection of tumors. Disparities in breast screening participation among socio‐demographic groups, including immigrants, have been reported in Canada. Our objectives were to: (1) assess breast screening participation and retention among immigrant and nonimmigrant women in British Columbia (BC), Canada; and (2) to characterize factors associated with screening among screening‐age recent immigrant women in BC. We examined 2 population‐based cohorts of women eligible for breast screening participation (537 783 women) and retention (281 052 women) using linked health and immigration data. Breast screening rates were presented according to socio‐demographic and health‐related variables stratified by birth country. Factors associated with screening among recent immigrant women were explored using Poisson regression. We observed marked variation in screening participation across birth country cohorts. Eastern European/Central Asian women showed low participation (37.9%) with rates from individual countries ranging from 35.0% to 49.0%. Participation rates for immigrant women from the most common birth countries, such as China/Macau/Hong Kong/Taiwan (45.7%), India (44.5%), the Philippines (45.9%), and South Korea (39.0%), were lower than the nonimmigrant rates (51.2%). Retention rates showed less variation by birth country; however, some disparities between immigrant and nonimmigrant groups persisted. Associations between screening indicators and study factors varied considerably across immigrant groups. Primary care physician visits were consistently positively associated with screening participation; this variable was also the only predictor associated with screening within each of the groups of recent immigrants. Our study provides unique data on both screening participation and retention among Canadian immigrant women compiled by individual country of birth. Our results are further demonstration that screening disparities exist among immigrant populations as well as in comparison with nonimmigrant women.

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Section: Methodsmentioning

confidence: 99%

Breast screening participation and retention among immigrants and nonimmigrants in British Columbia: A population‐based study

et al. 2018

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“…For each man who underwent vasectomy, we selected one man who did not, matching on age (within two years), comorbidity score (defined using the Johns Hopkins adjusted clinical groups case mix system),47 geographical area (defined by the first three digits of the postal code), and index date. The Johns Hopkins adjusted clinical case mix system was designed to predict healthcare use and considers the duration, severity, and intensity of service use related to both inpatient and outpatient claims, details of which have been provided elsewhere 48.…”

Section: Methodsmentioning

confidence: 99%

Vasectomy and risk of prostate cancer: population based matched cohort study

Nayan

Hamilton

Macdonald

et al. 2016

BMJ

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Objective To determine the association between vasectomy and prostate cancer, adjusting for measures of health seeking behaviour.Design Population based matched cohort study.Setting Multiple validated healthcare databases in Ontario, Canada, 1994-2012.Participants 326 607 men aged 20 to 65 who had undergone vasectomy were identified through physician billing codes and matched 1:1 on age (within two years), year of cohort entry, comorbidity score, and geographical region to men who did not undergo a vasectomy.Main outcomes measures The primary outcome was incident prostate cancer. Secondary outcomes were prostate cancer related grade, stage, and mortality.Results 3462 incident cases of prostate cancer were identified after a median follow-up of 10.9 years: 1843 (53.2%) in the vasectomy group and 1619 (46.8%) in the non-vasectomy group. In unadjusted analysis, vasectomy was associated with a slightly increased risk of incident prostate cancer (hazard ratio 1.13, 95% confidence interval 1.05 to 1.20). After adjustment for measures of health seeking behaviour, however, no association remained (adjusted hazard ratio 1.02, 95% confidence interval 0.95 to 1.09). Moreover, no association was found between vasectomy and high grade prostate cancer (adjusted odds ratio 1.05, 95% confidence interval 0.67 to 1.66), advanced stage prostate cancer (adjusted odds ratio 1.04, 0.81 to 1.34), or mortality (adjusted hazard ratio 1.06, 0.60 to 1.85).Conclusion The findings do not support an independent association between vasectomy and prostate cancer.

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“…Secondly, ADGs were analyzed using a previously validated scoring system utilizing weighted ADG scores and collapsing age and gender (Mortality Risk Score). 115 The Johns Hopkins ACG system has been well established as a tool to predict health care resource utilization, but more recent studies have also demonstrated its ability to predict mortality and long-term hospitalization. 116 Furthermore, ADGs accurately predict 1-year mortality in the general population and performed well compared to other established methods of comorbidity adjustment (Charlson comorbidity score).…”

Section: Johns Hopkins Adjusted Clinical Groups Systemmentioning

confidence: 99%

“…116 Furthermore, ADGs accurately predict 1-year mortality in the general population and performed well compared to other established methods of comorbidity adjustment (Charlson comorbidity score). 117 The…”

Section: Johns Hopkins Adjusted Clinical Groups Systemmentioning

confidence: 99%

886 Partial nephrectomy for the treatment of renal cell carcinoma and the risk of end stage renal disease

Yap¹,

Alibhai²,

Tomlinson³

et al. 2013

European Urology Supplements

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The surgical management of renal masses involves either radical nephrectomy (RN) or partial nephrectomy (PN). PN has been associated with better long-term renal function, and has also been linked to improved cardiac morbidity and overall survival. However, the relationship between treatment choice and definitive outcomes of chronic kidney disease (CKD) are lacking. Our aim was to examine whether PN is associated with a lower risk of end-stage renal disease (ESRD) requiring renal replacement therapy.We performed a population-based, retrospective cohort study with data from linked administrative databases in the province of Ontario, Canada. We included individuals with pathologically confirmed renal cell carcinoma (RCC) diagnosed between 1995 and 2010. Cox proportional hazards (PH) models, propensity score models, and competing risks models were used to assess the impact of treatment choice. PN compared to RN reduces the risk of ESRD requiring renal replacement therapy in a modern cohort of patients (2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010). PN is associated with a lower risk of new-onset CKD, lower risk of cardiac morbidity, and improved overall survival. We provide further evidence for the benefit of PN compared to RN, particularly related to definitive outcomes of renal failure.iii ACKNOWLEDGEMENTS

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Using the Johns Hopkins Aggregated Diagnosis Groups (ADGs) to Predict Mortality in a General Adult Population Cohort in Ontario, Canada

Cited by 321 publications

References 17 publications

Breast screening participation and retention among immigrants and nonimmigrants in British Columbia: A population‐based study

Breast screening participation and retention among immigrants and nonimmigrants in British Columbia: A population‐based study

Vasectomy and risk of prostate cancer: population based matched cohort study

886 Partial nephrectomy for the treatment of renal cell carcinoma and the risk of end stage renal disease

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