Using the Methodology of Systematic Review of Reviews for Evidence-Based Medicine

Hasanpoor, Edris; Hallajzadeh, Jamal; Siraneh, Yibeltal; Hasanzadeh, Ebrahim; Haghgoshayie, Elaheh

doi:10.4314/ejhs.v29i6.15

Cited by 20 publications

(17 citation statements)

References 23 publications

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“…This study was in response to the call and recommendation of a prior Ethiopian methodological study [ 34 ] that urged summary evidence on a certain health problem when there is more than one systematic review on that problem. Being the first of its kind in synthesizing the existing SRM reports about birth asphyxia in Ethiopia, this umbrella review has brought a comprehensive summary estimate of the problem.…”

Section: Discussionmentioning

confidence: 99%

“…Likewise, there is inconclusive reporting about the effects of different socio-demographic, antenatal, intra-natal and neonatal factors on birth asphyxia. Besides, this umbrella review was in response to the call and recommendation of a prior Ethiopian methodological study [ 34 ]. Therefore, the aim of this umbrella review was to summarize the heterogeneous findings of the 4 SRM studies [ 30 , 31 , 32 , 33 ] about birth asphyxia into a single comprehensive document where the results of these reviews can be compared and contrasted.…”

Section: Introductionmentioning

confidence: 99%

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The state of birth asphyxia in Ethiopia: An umbrella review of systematic review and meta-analysis reports, 2020

Bayih

Birhane

Belay

et al. 2021

Heliyon

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The state of birth asphyxia in Ethiopia: An umbrella review of systematic review and meta-analysis reports, 2020

Bayih

Birhane

Belay

et al. 2021

Heliyon

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“…A systematic review of reviews was conducted in order to gather existing evidence on community mobilization strategies that strengthen support for appropriate and timely use of ANC/PNC, including use of ANC in the first trimester of pregnancy. This approach summarizes the findings of published reviews to synthesize existing evidence in an overview that can inform future guidelines, programmes, and policy [ 28 - 30 ]. As there are already existing systematic reviews on community mobilization within reproductive, maternal, newborn and child health (RMNCH), this methodology was chosen to provide high level evidence on such strategies for ANC/PNC and to reveal where findings are consistent [ 31 , 32 ].…”

Section: Methodsmentioning

confidence: 99%

Community mobilization to strengthen support for appropriate and timely use of antenatal and postnatal care: A review of reviews

et al. 2021

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Background Antenatal care (ANC) and postnatal care (PNC) are critical opportunities for women, babies and parents/families to receive quality care and support from health services. Community-based interventions may improve the accessibility, availability, and acceptance of this vital care. For example, community mobilization strategies have been used to involve and collaborate with women, families and communities to improve maternal and newborn health. Objective To synthesize existing reviews of evidence on community mobilization strategies that strengthen support for appropriate and timely use of ANC and PNC. Methods Six databases (MEDLINE, Embase, CINAHL, PsychINFO, Cochrane Library, PROSPERO) were searched for published reviews that describe community mobilization related strategies for ANC and/or PNC. Reviews were eligible for inclusion if they described any initiatives or strategies targeting the promotion of ANC and/or PNC uptake that included an element of community mobilization in a low- or middle-income country (LMIC), published after 2000. Included reviews were critically appraised according to the Joanna Briggs Institute (JBI) Checklist for Systematic Reviews and Evidence Syntheses. This review of reviews was conducted following JBI guidelines for undertaking and reporting umbrella reviews. Results In total 23 papers, representing 22 reviews were included. While all 22 reviews contained some description of community mobilization and ANC/PNC, 13 presented more in-depth details on the community mobilization processes and relevant outcomes. Seventeen reviews focused on ANC, four considered both ANC and PNC, and only one focused on PNC. Overall, 16 reviews reported at least one positive association between community mobilization activities and ANC/PNC uptake, while five reviews presented primary studies with no statistically significant change in ANC uptake and one included a primary study with a decrease in use of antenatal facilities. The community mobilization activities described by the reviews ranged from informative, passive communication to more active, participatory approaches that included engaging individuals or consulting local leaders and community members to develop priorities and action plans. Conclusions While there is considerable momentum around incorporating community mobilization activities in maternal and newborn health programs, such as improving community support for the uptake of ANC and PNC, there is limited evidence on the processes used. Furthermore, the spectrum of terminology and variation in definitions should be harmonized to guide the implementation and evaluation efforts.

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“…Second, conducting a systematic review that combines RCTs with a systematic review and meta-analysis may be regarded as not following best practice for conducting a systematic reviews of systematic reviews; 56 however, this was the most appropriate design to answer the primary objectives of our study. Furthermore, the authors could not synthesize evidence related to efficacy outcomes since studies with this focus were sparse.…”

Section: Limitationsmentioning

confidence: 99%

Effect of Pharmacogenetic-Based Decision Support Tools in Improving Depression Outcomes: A Systematic Review

Aboelbaha¹,

Zolezzi²,

Elewa³

2021

NDT

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Objective: Evidence supporting the utility of pharmacogenetic (PGX) tests in depression is scarce. The main objectives of this study were to summarize, update, and assess the quality of the available evidence regarding PGX testing in depression as well as estimating the impact of using PGX testing tools in depression outcomes in the Middle East/North Africa (MENA) region. Methodology: Scientific databases were systematically searched from inception to June 30, 2020 for systematic reviews and randomized controlled trials (RCTs) assessing the clinical utility of PGX tests in the treatment of depression. Meta-analyses only and RCTs that were included in eligible systematic reviews were excluded. The quality of the eligible studies was assessed using the Crowe Critical Appraisal Tool (CCAT). Results: Six systematic reviews and three RCTs met the inclusion criteria and were included in this study. The results of the systematic reviews provided weak evidence on the efficacy of PGX testing, especially in patients with moderate-severe depression at 8 weeks. In addition, there was a lack of evidence regarding safety outcomes. Newer RCTs with better quality showed clinical promise regarding efficacy outcomes, especially in patients with gene-drug interactions. No evidence was found regarding PGX testing impact in the MENA region. Conclusion:This systematic review is an update and summary of the available literature on the clinical utility of PGX testing in depression. The findings of this study demonstrate that PGX testing prior to treatment initiation or during the course of therapy may improve efficacy outcomes. Further studies are warranted to assess the impact of PGX testing on safety outcomes.

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Using the Methodology of Systematic Review of Reviews for Evidence-Based Medicine

Abstract: Systematic Review of Reviews without abstract. Authors' invited you to read the whole review article since it is short.

Cited by 20 publications

References 23 publications

The state of birth asphyxia in Ethiopia: An umbrella review of systematic review and meta-analysis reports, 2020

The state of birth asphyxia in Ethiopia: An umbrella review of systematic review and meta-analysis reports, 2020

Community mobilization to strengthen support for appropriate and timely use of antenatal and postnatal care: A review of reviews

Effect of Pharmacogenetic-Based Decision Support Tools in Improving Depression Outcomes: A Systematic Review

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