Using the multiphase optimization strategy (MOST) framework to optimize an intervention to increase COVID-19 testing for Black and Latino/Hispanic frontline essential workers: A study protocol

Gwadz, Marya; Cleland, Charles M.; Lizardo, Maria; Hawkins, Robert L.; Bangser, Greg; Parameswaran, Lalitha; Stanhope, Victoria; Robinson, Jennifer A.; Karim, Shristi; Hollaway, Tierra; Ramirez, Paola G; Filippone, Prema; Ritchie, Amanda S.; Banfield, Angela; Silverman, Elizabeth

doi:10.1186/s12889-022-13576-0

Cited by 3 publications

(1 citation statement)

References 86 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As an exploratory study based on a relatively small sample, this research has inherent limitations regarding generalizability. Future research, some of which is currently in progress by our research team [52], should test interventions that incorporate "trustworthy" characteristics identified in this study to determine their effectiveness at both increasing trust and vaccine confidence. The extent to which our findings apply to distrust and hesitancy surrounding other types of vaccines is also unknown.…”

Section: Discussionmentioning

confidence: 99%

Toward trustworthy COVID-19 interventions: Building vaccine trust through community-university partnerships

Bray,

Jervis,

Janitz

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Prior research identifies trust as critical to increase vaccine acceptance and uptake. However, few intervention studies have sought to develop or test strategies for bolstering vaccine-related trust. To address this gap, this exploratory study identifies features of COVID-19 vaccine hesitancy interventions that can promote or undermine trust across three interconnected domains: institutional, interpersonal, and product (the vaccine itself). We draw on focus groups (N = 27 participants) with community and university partners involved with hosting COVID-19 testing and vaccine events in underserved Oklahoma communities. Focus groups explored participants’ experiences serving community health needs and elicited feedback on proposed vaccine hesitancy interventions. Proposed interventions included two technology-based strategies (text message reminders and tablet-based testimonials and education) and one dialogue-based strategy (anti-body test interpretation). We find that community partners perceived local universities as trustworthy institutions because of their association with popular sports programs, academic credentials, and proximity, creating opportunities to address vaccine-related distrust through community-university partnerships. The most promising intervention strategies for building interpersonal trust included engaging in one-on-one dialogue and using autonomy enhancing approaches. Finally, interventions that successfully encouraged vaccine trust did so by incorporating personalized health information about individuals’ potential level of protection and susceptibility to the COVID-19 virus. These findings can inform future public health efforts to create trustworthy vaccine hesitancy interventions.

show abstract

Section: Discussionmentioning

confidence: 99%

Toward trustworthy COVID-19 interventions: Building vaccine trust through community-university partnerships

Bray,

Jervis,

Janitz

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

show abstract

Increasing pre-exposure prophylaxis (PrEP) in primary care: A study protocol for a multi-level intervention using the multiphase optimization strategy (MOST) framework

Lockhart,

Turner,

Guastaferro

et al. 2024

Contemporary Clinical Trials

View full text Add to dashboard Cite

CATCH-UP vaccines: protocol for a randomized controlled trial using the multiphase optimization strategy (MOST) framework to evaluate education interventions to increase COVID-19 vaccine uptake in Oklahoma

Janitz,

Neil,

Bray

et al. 2023

BMC Public Health

View full text Add to dashboard Cite

Background Oklahoma’s cumulative COVID-19 incidence is higher in rural than urban counties and higher than the overall US incidence. Furthermore, fewer Oklahomans have received at least one COVID-19 vaccine compared to the US average. Our goal is to conduct a randomized controlled trial using the multiphase optimization strategy (MOST) to test multiple educational interventions to improve uptake of COVID-19 vaccination among underserved populations in Oklahoma. Methods Our study uses the preparation and optimization phases of the MOST framework. We conduct focus groups among community partners and community members previously involved in hosting COVID-19 testing events to inform intervention design (preparation). In a randomized clinical trial, we test three interventions to improve vaccination uptake: (1) process improvement (text messages); (2) barrier elicitation and reduction (electronic survey with tailored questions/prompts); and (2) teachable moment messaging (motivational interviewing) in a three-factor fully crossed factorial design (optimization). Discussion Because of Oklahoma’s higher COVID-19 impact and lower vaccine uptake, identifying community-driven interventions is critical to address vaccine hesitancy. The MOST framework provides an innovative and timely opportunity to efficiently evaluate multiple educational interventions in a single study. Trial Registration ClinicalTrials.gov: NCT05236270, First Posted: February 11, 2022, Last Update Posted: August 31, 2022.

show abstract

Using the multiphase optimization strategy (MOST) framework to optimize an intervention to increase COVID-19 testing for Black and Latino/Hispanic frontline essential workers: A study protocol

Cited by 3 publications

References 86 publications

Toward trustworthy COVID-19 interventions: Building vaccine trust through community-university partnerships

Toward trustworthy COVID-19 interventions: Building vaccine trust through community-university partnerships

Increasing pre-exposure prophylaxis (PrEP) in primary care: A study protocol for a multi-level intervention using the multiphase optimization strategy (MOST) framework

CATCH-UP vaccines: protocol for a randomized controlled trial using the multiphase optimization strategy (MOST) framework to evaluate education interventions to increase COVID-19 vaccine uptake in Oklahoma

Contact Info

Product

Resources

About