Using the Patient Health Questionnaire (PHQ-9) and the Edinburgh Postnatal Depression Scale (EPDS) to assess suicidal ideation among pregnant women in Lima, Peru

Qu, Zhong; Gelaye, Bizu; Rondón, Marta B.; Sánchez, Sixto E.; Simon, Gregory E.; Henderson, David C.; Barrios, Yasmin V.; Sanchez, Sixto E.; Williams, Michelle A.

doi:10.1007/s00737-014-0481-0

Cited by 76 publications

(57 citation statements)

References 42 publications

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“…The two most widely used screeners to assess suicidal ideation are item 9 of the Patient Health Questionnaire-9 scale (PHQ-9) and item 10 of the Edinburgh Postnatal Depression Scale (EPDS). Specifically, item 9 of the PHQ-9 assesses suicidal ideation over the past 14 days and item 10 of the EPDS assesses suicidal ideation over the past 7 days (Zhong et al, 2014). Zhong et al (Zhong et al, 2014) evaluated the concordance of these two items among pregnant women in Peru and found high concordance (84.2%), but moderate agreement (the Cohen’s kappa=0.42) for the two items when assessed in the same population.…”

Section: Resultsmentioning

confidence: 99%

“…Specifically, item 9 of the PHQ-9 assesses suicidal ideation over the past 14 days and item 10 of the EPDS assesses suicidal ideation over the past 7 days (Zhong et al, 2014). Zhong et al (Zhong et al, 2014) evaluated the concordance of these two items among pregnant women in Peru and found high concordance (84.2%), but moderate agreement (the Cohen’s kappa=0.42) for the two items when assessed in the same population. Antepartum suicidal ideation was reported among 15.8% participants on PHQ-9 and 8.8% on EPDS (Zhong et al, 2014).…”

Section: Resultsmentioning

confidence: 99%

“…Zhong et al (Zhong et al, 2014) evaluated the concordance of these two items among pregnant women in Peru and found high concordance (84.2%), but moderate agreement (the Cohen’s kappa=0.42) for the two items when assessed in the same population. Antepartum suicidal ideation was reported among 15.8% participants on PHQ-9 and 8.8% on EPDS (Zhong et al, 2014). Another group of investigators compared item 10 of the EPDS to the Mood Spectrum Self-Report (MOODS-SR) (Mauri et al, 2012) in a sample of pregnant women in Italy.…”

Section: Resultsmentioning

confidence: 99%

“…The few screening instruments that exist are limited as they were primarily developed to measure antepartum and postpartum depression, not antepartum suicidal ideation. Given that a substantial proportion of women with suicidal ideation do not meet clinical thresholds of depression (Zhong et al, 2014), and given the current burden of suicidal ideation, efforts to design and enhance the psychometric properties and validity of antepartum suicidal ideation screening questionnaires are warranted.…”

Section: Resultsmentioning

confidence: 99%

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Suicidal ideation in pregnancy: an epidemiologic review

Gelaye

Kajeepeta

Williams

2016

Arch Womens Ment Health

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138

125

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Objective Suicidal behaviors are the leading causes of injury and death worldwide, and are leading causes of maternal deaths in some countries. One of the strongest risk factors, suicidal ideation, is considered a harbinger and distal predictor of later suicide attempt and completion, and also presents an opportunity for interventions prior to physical self-harm. The purpose of this systematic epidemiologic review is to synthesize available research on antepartum suicidal ideation. Data sources Original publications were identified through searches of the electronic databases using the search terms pregnancy, pregnant women, suicidal ideation, and pregnan* and suicid* as root searches. We also reviewed references of published articles. Study Selection We identified a total of 2,626 articles through the electronic database search. After irrelevant and redundant articles were excluded 57 articles were selected. The selected articles were original articles that focused on pregnancy and suicidal ideation. Results Of the 57 included articles, 20 reported prevalence, 26 reported risk factors, 21 reported consequences of antepartum suicidal ideation, and 5 reported on screening measures. Available evidence indicates that pregnant women are more likely than the general population to endorse suicidal ideation. Additionally, a number of risk factors for antepartum suicidal ideation were identified including intimate partner violence, <12 years education, and major depressive disorder. Conclusion There is a need for enhanced screening for antepartum suicidal ideation. The few screening instruments that exist are limited as they were primarily developed to measure antepartum and postpartum depression. Given a substantial proportion of women with suicidal ideation do not meet clinical thresholds of depression and given the stress–diathesis model that shows susceptibility to suicidal behavior independent of depressive disorders, innovative approaches to improve screening and detection of antepartum suicidal ideation are urgently needed.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Suicidal ideation in pregnancy: an epidemiologic review

Gelaye

Kajeepeta

Williams

2016

Arch Womens Ment Health

Self Cite

138

125

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“…If the response was “several days,” “more than half the days,” or “nearly every day,” suicidal ideation was coded as “yes.” Participants responding “not at all” were classified as “no” for suicidal ideation. (Zhong et al, 2015) The Cronbach's alpha of PHQ-9 in our study sample is 0.82. Participants with PHQ-9 score ≥10 were categorized as showing depression.…”

Section: Methodsmentioning

confidence: 63%

Trauma and traumatic stress in a sample of pregnant women

Gelaye

Basu

et al. 2017

Psychiatry Research

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Objective To examine the construct validity of the 9 item Traumatic Events Questionnaire (TEQ) and to evaluate the extent to which experiences of trauma assessed using the TEQ are associated with symptoms of psychiatric disorders among 3,342 pregnant women in Lima, Peru. Methods Symptoms of depression were assessed using the Patient Health Questionnaire-9 (PHQ-9) and Edinburgh Postnatal Depression Scale (EPDS) while the PTSD Checklist-civilian (PCL-C) and Generalized Anxiety Disorder-7 (GAD-7) were used to assess symptoms of PTSD and generalized anxiety. Hierarchical logistic regression procedures were used to evaluate relations between TEQ and symptoms of psychiatric disorders. Results The majority of participants (87.8%) experienced at least one traumatic event (mean=2.5 events). The trauma occurrence score was moderately correlated with symptoms of PTSD (PCL-C: rho=0.38, P-value<0.0001), depression (EPDS: rho=0.31, P-value<0.0001; PHQ-9: rho=0.20, P-value <0.0001), and GAD (GAD-7: rho=0.29, P-value<0.0001). Stronger correlations were observed between the trauma intensity score with symptoms of psychiatric disorders (PCL-C: rho=0.49, P-value<0.0001; EPDS: rho=0.36, P-value<0.0001; PHQ-9: rho=0.31, P-value<0.0001; GAD-7: rho=0.39 P-value<0.0001). Conclusion Given the high burden of trauma experiences and the enduring adverse consequences on maternal and child health, there is an urgent need for integrating evidence-based trauma informed care programs in obstetrical practices serving Peruvian patients.

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Effect of Dexmedetomidine on Postpartum Depression in Women With Prenatal Depression

Zhou,

Bai,

Zhang

et al. 2024

JAMA Netw Open

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ImportancePostpartum depression (PPD) is emerging as a major public health problem worldwide. Although the particular period and context in which PPD occurs provides an opportunity for preventive interventions, there is still a lack of pharmacologic prevention strategies for PPD.ObjectiveTo assess the efficacy and safety of dexmedetomidine for prevention of PPD among women with prenatal depression undergoing cesarean delivery.Design, Setting, and ParticipantsThis randomized clinical trial enrolled 338 women who screened positive for prenatal depression at 2 hospitals in Hunan, China from March 28, 2022, to April 16, 2023. Women with an Edinburgh Postnatal Depression Scale score of more than 9 who were 18 years of age or older and were scheduled for elective cesarean delivery were eligible.InterventionsEligible participants were randomly assigned in a 1:1 ratio to either the dexmedetomidine group or the control group via centrally computer-generated group randomization. Dexmedetomidine, 0.5 μg/kg and 0.9% saline were intravenously infused for 10 minutes after delivery in the dexmedetomidine and control groups, respectively. After infusion, sufentanil or dexmedetomidine plus sufentanil was administered via patient-controlled intravenous analgesia for 48 hours in the control group and dexmedetomidine group, respectively.Main Outcomes and MeasuresThe primary outcome was positive PPD screening results at 7 and 42 days post partum, defined as a postpartum Edinburgh Postnatal Depression Scale score of more than 9. Analysis was on an intention-to-treat basis.ResultsAll 338 participants were female, with a mean (SD) age of 31.5 (4.1) years. Positive PPD screening incidence at 7 and 42 days post partum in the dexmedetomidine group vs the control group was significantly decreased (day 7, 21 of 167 [12.6%] vs 53 of 165 [32.1%]; risk ratio, 0.39 [95% CI, 0.25-0.62]; P &lt; .001; day 42, 19 of 167 [11.4%] vs 50 of 165 [30.3%]; risk ratio, 0.38 [95% CI, 0.23-0.61]; P &lt; .001). The dexmedetomidine group showed no significant difference in adverse events vs the control group (46 of 169 [27.2%] vs 33 of 169 [19.5%]; P = .10), but the incidence of hypotension increased (31 of 169 [18.3%] vs 16 of 169 [9.5%]; risk ratio, 2.15 [95% CI, 1.13-4.10]; P = .02).Conclusions and RelevanceDexmedetomidine administration in the early postpartum period significantly reduced the incidence of a positive PPD screening and maintained a favorable safety profile.Trial RegistrationChinese Clinical Trial Registry Identifier: ChiCTR2200057213

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Using the Patient Health Questionnaire (PHQ-9) and the Edinburgh Postnatal Depression Scale (EPDS) to assess suicidal ideation among pregnant women in Lima, Peru

Cited by 76 publications

References 42 publications

Suicidal ideation in pregnancy: an epidemiologic review

Suicidal ideation in pregnancy: an epidemiologic review

Trauma and traumatic stress in a sample of pregnant women

Effect of Dexmedetomidine on Postpartum Depression in Women With Prenatal Depression

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