Using ultrasound in the clinical management of placental implantation abnormalities

Prenatal diagnosis and management of vasa previa in twin pregnancies: a case series and systematic review

“…7 Approximately 90% of women presenting with a VP also have a velamentous cord insertion (VCI) and 3-4% of women presenting with a VCI have a VP. 8 Unlike the single umbilical artery cord which is routinely recorded by midwives at birth, these cord anomalies are only recorded when associated with perinatal complications and the placental is examined by a pathologist.…”

“…Both cord anomalies are 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 5 5 low-lying placenta. [1][2][3][4][5][6][7][8] VCI and VP type I are also more common in twin pregnancies and monochorionicity doubles the risk for VCI compared to dichorinicity. 11,12 Maternal smoking has been recently reported as a risk factor for VCI and thus potentially of VP.…”

“…[3][4][5][6]8,19 Twin pregnancies are associated with specific obstetric complications and in particular with a higher incidence of premature delivery. 20 Like singletons, twins presenting with VP have very poor outcomes when antenatal diagnosis is not made before the onset of labour.…”

Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics

“…Instead, ultrasonography and maternal serum protein markers have been pursued to noninvasively monitor placental function during pregnancy (3,4). It has been shown that the placenta is the major source of circulating cell-free fetal nucleic acids in maternal plasma (5)(6)(7).…”

Cervical Length in Patients at Risk for Placenta Accreta

“…Prospective studies performed in women with nonadherent placenta previa showed that a cervical length of 3 cm or less during a third‐trimester ultrasound examination was associated with higher rates of bleeding, contractions, and preterm delivery, as hemorrhage in this setting results from the tearing of placental attachments in the lower uterine segment during labor. Most recently, these studies formed the basis of recommendations for the antepartum management and delivery timing of women with placenta previa, with or without placenta accreta . However, it is our clinical observation that women with placenta accreta sometimes have less bleeding during the third trimester than women with nonadherent low‐lying or placenta previa.…”