In this paper, we integrate WebML, a high-level model and technology for building server-side Web applications, with UML-Guide, a UML-based system that generates client-side guides for the adaptation of Web applications. The combination of the two systems is shown at work on an e-learning scenario: WebML is the basis of the specification of a generic e-learning system, collecting a large number of learning objects, while UML-Guide is used for building company-specific e-learning curricula. The resulting system can be considered an "adaptive hypermedia generator" in full strength, whose potential expressive power goes beyond the experiments reported in this paper.