Study setting and selection of patientsThe out-of-hours healthcare system in the Netherlands and data collection of this study have been published previously. 15 In summary, all contacts of children <16 years that had taken place at five GP cooperatives (GPCs) of the Rotterdam Rijnmond-district (collaboration of >250 GP-practices) between March 2008 and February 2009 were selected. Eligible contacts were those concerning children who had a face-to-face consultation with the GP and reported fever as the reason for contact, had fever within the 24 hours before contact, or had a (rectal or tympanic) temperature >38˚C measured at the GPC. Re-contacts for the same problem within 7 days of the initial presentation were excluded from the main analyses.