Uso de anticoagulantes orales en situaciones clínicas complejas con fibrilación auricular

Gullón, Alejandra; Fuentes, D. Sánchez; López-de-Sá, Esteban; Martí‐Almor, Julio; Barón-Esquivias, Gonzalo; López, José Darío Sánchez; Muruaga, María del Mar Contreras; Fernández, Carmen Suárez

doi:10.1016/s0025-7753(18)30666-3

Cited by 2 publications

(1 citation statement)

References 163 publications

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“…While studies differ with respect to the figures they report, overall, anticoagulation rates in elderly patients with AF vary from only 25 to 75%. In clinical practice, it has been shown that anticoagulation does not depend so much on thromboembolic risk or bleeding as on other factors [36][37][38][39]. In fact, several studies have analyzed the main independent factors that favor not anticoagulating the elderly patient, namely, advanced age (anticoagulation therapy is prescribed less frequently with age), the degree of dependence, cognitive impairment, frailty and the risk of falls [40,41].…”

Section: Assessment Of the Risk Of Stroke And Bleeding In The Elderly Patientmentioning

confidence: 99%

The problem of underdosing with direct-acting oral anticoagulants in elderly patients with nonvalvular atrial fibrillation

2020

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Unless contraindicated, anticoagulant therapy should be prescribed to elderly patients with atrial fibrillation. Direct-acting oral anticoagulants (DOACs) are superior to vitamin K antagonists for preventing stroke. This, together with their higher net clinical benefit, makes DOACs the treatment of choice in this population. However, due to the concerns about bleeding and the need for dose adjustment based on clinical variables, underdosing of DOACs is common and the risk of stroke high. Drugs with more easily adjusted doses are likely associated with a lower risk of dosing errors and, therefore, a greater protective effect. Correct dosing can ensure a maximal net benefit of DOACs in elderly patients with atrial fibrillation.

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Section: Assessment Of the Risk Of Stroke And Bleeding In The Elderly Patientmentioning

confidence: 99%

The problem of underdosing with direct-acting oral anticoagulants in elderly patients with nonvalvular atrial fibrillation

2020

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Uso de tratamiento anticoagulante en los enfermos con fibrilación auricular o flutter auricular de mayor edad que ingresan en el servicio de medicina interna de un hospital de segundo nivel

Mora

Ferrando

Pérez

et al. 2021

Medicina Clínica Práctica

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Uso de anticoagulantes orales en situaciones clínicas complejas con fibrilación auricular

Cited by 2 publications

References 163 publications

The problem of underdosing with direct-acting oral anticoagulants in elderly patients with nonvalvular atrial fibrillation

The problem of underdosing with direct-acting oral anticoagulants in elderly patients with nonvalvular atrial fibrillation

Uso de tratamiento anticoagulante en los enfermos con fibrilación auricular o flutter auricular de mayor edad que ingresan en el servicio de medicina interna de un hospital de segundo nivel

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