Uso terapêutico de tecidos e órgãos humanos para transplantes: eventos adversos e ações de biovigilância

Treviso, Patrícia; Schirmer, Janine; Mendes, Karina Dal Sasso; Fernandes, Sabrina Alves; Silveira, Andresa Thomé; Roza, Bartira de Aguiar

doi:10.19175/recom.v11i0.4044

Cited by 4 publications

(9 citation statements)

References 5 publications

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“…Standardization also allows results and strategies to be compared both nationally and internationally, seeking better results and data reliability, with the aim of improving the quality and safety of donation and transplantation processes. 12 Despite the importance of knowing the adverse events in biovigilance, these data are still scarce. There are organizational, political, and institutional factors that can interfere with their collection and dissemination.…”

Section: Discussionmentioning

confidence: 99%

“…Regarding the research, it was noticed a higher volume of notifications in the years 2016, 34.6% (18), and 2018, 32.7% (17), however in 2016 40,788 cell, tissue and organ transplants were performed, in 2017 41,693, in 2018 38,547 and in 2019 38,483. [12][13][14][15][16] That is, despite the high number of procedures performed, the rate of incident notifications is still low.…”

Section: Discussionmentioning

confidence: 99%

“…This data may be related to the fact that the transplant recipient is more vulnerable, corroborating another published study and the first report of adverse events data in biovigilance in Brazil. 12,18 As for the severity of the adverse events under study, it is noted that in the state of São Paulo most notifications were classified as moderate, followed by deaths, severe, and mild. This information is not similar to that seen in the national report, since in Brazil the most common notifications are mild and moderate.…”

Section: Discussionmentioning

confidence: 99%

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Adverse Events in Cells, Tissues, and Organs Donation and Transplantation

Paim

Roza

Schirmer

2022

BJT

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Abstract:Objective: To characterize adverse events in cells, tissue, and organs donation, and transplantation notified in the state of São Paulo, Brazil. Method: Descriptive study with quantitative approach. Data provided by Transplantation Central of São Paulo from the “Individual notification form of adverse reactions in Biovigilance”, of the FormSUS platform, between 2016 and 2019, and categorized according to the nomenclature recommended by the World Health Organization regarding nature and type of event, severity, and imputability. Analysis was performed using descriptive statistics. Results: Fifty-two notifications were characterized, 90.4% related to the recipient, 78.8% from allogeneic procedures, 48.2% related to organs, and 44.2% to hematopoietic stem cells. The causes of notifications were infections (55.7%), other ones (30.8%), and neoplasms (13.5%). Most of the events were moderate (44.3%), and 36.5% were confirmed. Conclusion: It was possible to identify the scenario of biovigilance in the state, visualizing that the main adverse events are related to the receptor from allogeneic procedures. In addition, the major cause of adverse events in the state of São Paulo are infections, especially those caused by Mycobacterium tuberculosis and Klebsiellapneumoniae. The characterization of these events can support the development of safety strategies to prevent recurrence, the realization of institutional training and public policies to encourage notification and expand the understanding of adverse events in this scenario, since it is only possible to ensure quality and safety in health care, especially in the context of donations and transplants, from the recognition of reality.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Adverse Events in Cells, Tissues, and Organs Donation and Transplantation

Paim

Roza

Schirmer

2022

BJT

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“…La estandarización también permite que resultados y estrategias sean comparados tanto a nivel nacional como internacional, buscando mejores resultados y confiabilidad de los datos, con el objetivo de mejorar la calidad y la seguridad de los procesos en donación y transplantes. 12 A pesar de la importancia de conocer los eventos adversos en biovigilancia, esos datos aún son escasos. Hay factores organizativos, políticos e institucionales que pueden interferir en su obtención y divulgación.…”

Section: Discussionunclassified

“…En lo referente a la investigación, se percibió mayor volumen de notificaciones en los años 2016, 34,6% (18), y 2018, 32,7% (17), sin embargo, en el 2016 fueron realizados 40.788 transplantes de células, tejidos y órganos, en el 2017 41.693, en el 2018 38.547 y en el 2019 38.483. [12][13][14][15][16] O sea, a pesar del alto número de procedimientos realizados, la tasa de notificaciones de incidentes aún es baja.…”

Section: Discussionunclassified

Eventos Adversos en la Donación y Trasplante de Células, Tejidos y Órganos

Paim

Roza

Schirmer

2022

BJT

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Resumen:Objetivo: Caracterizar los eventos adversos en la donación y trasplante de células, tejidos y órganos informados en el estado de São Paulo. Método: Estudio descriptivo con enfoque cuantitativo. Los datos fueron proporcionados por el Centro Estatal de Trasplantes del estado de São Paulo, a partir del “Formulario de notificación individual de reacciones adversas en Biovigilancia” de la plataforma FormSUS entre 2016 y 2019. Categorizados según la nomenclatura recomendada por la Organización Mundial de la Salud en cuanto a: naturaleza y tipo de evento, gravedad y imputabilidad. Análisis realizado mediante estadística descriptiva. Resultados: se caracterizaron 52 notificaciones, 90,4% relacionadas con el receptor, 78,8% de procedimientos alogénicos, 48,2% relacionadas con órganos y 44,2% con células madre hematopoyéticas. Las causas de notificación fueron infecciones (55,7%), otras causas (30,8%) y neoplasias (13,5%). La mayoría de los eventos informados tuvieron resultados moderados (44,3 %) y el 36,5 % de los informes se consideraron confirmados. Conclusión: Se logró identificar el escenario de biovigilancia en el estado, visualizando que los principales eventos adversos están relacionados al receptor de procedimientos alogénicos. Además, la mayor causa de eventos adversos en el estado de São Paulo son las infecciones, especialmente las causadas por M. tuberculosis y K. pneumoniae. La caracterización de estos eventos puede apoyar el desarrollo de estrategias de seguridad para prevenir la recurrencia, la realización de capacitaciones institucionales y políticas públicas para incentivar la notificación y ampliar la comprensión de los eventos adversos en este escenario. Ya que sólo es posible garantizar la calidad y la seguridad en la atención sanitaria, especialmente en el contexto de las donaciones y trasplantes, desde el reconocimiento de la realidad.

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Social Representation of the Nurse in the Organ Donation Process

Andrade¹,

Cardoso²

2023

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Brazil is a world reference in the field of transplants and has the largest public transplant system in the world. It is known to a large part of the population that thousands of people live with the hope of carrying out the transplant, however, the reality shows a discrepancy between the number of people waiting for an organ and the number of potential donors. Objective: to identify the importance of organ donation and the role of nurses (a) in front of a multidisciplinary team in the process of capturing organs and tissues for donation and transplantation. Materials and method: This is a narrative bibliographic review study. And it had as inclusion criteria the search for material published in the period from 2019 to 2022, in Portuguese and English languages in virtual databases such as BVS and Bireme. Eighteen publications were selected for data collection. Results: three subjects were listed in category format, such as Brazilian guidelines for organ donation; Biovigilance in organ donation; Social representation of nurses in organ donation. Conclusion: It is essential to look at the professional with the aim of offering constant and systematic technical and emotional support, which contributes to the care provided to family members.

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Uso terapêutico de tecidos e órgãos humanos para transplantes: eventos adversos e ações de biovigilância

Cited by 4 publications

References 5 publications

Adverse Events in Cells, Tissues, and Organs Donation and Transplantation

Adverse Events in Cells, Tissues, and Organs Donation and Transplantation

Eventos Adversos en la Donación y Trasplante de Células, Tejidos y Órganos

Social Representation of the Nurse in the Organ Donation Process

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