Uso terapêutico de ultrassom e microbolhas na recanalização de infarto agudo do miocárdio

Abstract

Correlação entre o % da área infartada pela ecocardiografia e a redução do segmento ST no ECG .

Therapeutic Use of Ultrasound Associated to Microbubbles in Acute Myocardial Infarction

“…André Luiz Cerqueira Almeida Hospital Dom Pedro de Alcântara; Santa Casa de Misericórdia de Feira de Santana, Feira de Santana, BA -Brazil This issue of Arquivos Brasileiros de Cardiologia Imagem Cardiovascular presents the important article "Ultrasound and microbubbles for coronary artery recanalization in acute myocardial infarction." 1 The first author of the study is Dr. Bruno Garcia Tavares and the last one is Dr. Wilson Mathias Jr., both from Instituto do Coração da Faculdade de Medicina da Universidade de São Paulo and Grupo Fleury, São Paulo, Brazil, with participation of Dr. Thomas Richard Porter, from the University of Nebraska. It is a pilot study that aimed to evaluate the effectiveness of intravenous microbubbles (MB) and ultrasound (US), a procedure known as sonothrombolysis on the initial rates of recanalization of coronary arteries in patients with acute ST segment elevation myocardial infarction (STEMI).…”

“…5 Xie F. et al showed that MB associated with US improves microvascular flow in the peri-infarcted region in pigs with STEMI. 11 In the study by Tavares et al, 1 the authors studied 24 patients in the acute phase of STEMI. These were randomized to three groups: the first one used MB, in continuous infusion, associated with US with mechanical index (MI) and high pulse duration between 4 and 20 μseg (N = 7); the second one, MB + US with repetitive pulses of high MI with pulse duration <2 μseg (n = 8).…”