Uterine Artery Embolization in Women with Symptomatic Cervical Leiomyomata: Efficacy and Safety

Bruijn, Annefleur M. de; Adriaansens, Sven-Ole J. H.; Smink, Marieke; Venmans, A.; Hehenkamp, Wouter J.K.; Smeets, Albert J.; Lopez, Anthony; Huirne, Judith A.F.; Lohle, Paul N.M.

doi:10.1007/s00270-018-2081-2

Cited by 8 publications

(4 citation statements)

References 23 publications

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“…The description of the symptoms was retrievable in 32 studies [ 8 , 17 , 19 , 20 , 21 , 22 , 24 , 25 , 29 , 33 , 34 , 35 , 36 , 37 , 38 , 40 , 41 , 42 , 43 , 44 ] enrolling 130 patients.…”

Section: Resultsmentioning

confidence: 99%

Current Treatment Options for Cervical Leiomyomas: A Systematic Review of Literature

et al. 2021

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Background and objectives: Cervical leiomyomas are a rare benign disease. Although they are mainly treated surgically, currently, there is not a standardized treatment for cervical leiomyomas. This study aims to summarize current literature evidence about treatment options for cervical leiomyomas. Materials and methods: A systematic research of the literature was conducted in Scopus, PubMed/MEDLINE, ScienceDirect, and the Cochrane Library, including observational prospective and retrospective studies, case series and case reports. We collected data regarding studies related to treatment options for cervical leiomyomas, evaluating the following aspects: study design, population, treatment type, rate of surgical complications, and fertility outcome. Results: According to literature research, 38 articles were included. Among 214 patients, the weighted average age was 39.4 years-old; 23 patients were pregnant. Most of the leiomyomas (78%) were extracervical; in 22% of cases (29 patients) were intracervical; 188 patients (88%) received surgical treatment, 6 (3%) received exclusive conservative management and 21 (10%) underwent interventional radiology treatment. One hundred twenty-seven patients (67.5%) underwent myomectomy, while 54 (28.7%) and 7 (3.7%) hysterectomy and trachelectomy, respectively. Cervical myomectomy was performed by open surgery in 21 out of 127 cases (16.5%), while in 92 (72.4%) and 6 (4.7%) patients the surgical approach was performed by traditional and robot-assisted laparoscopy, respectively. The total rate of surgical complications was 5.6%. Conclusion: Surgery is the primary therapeutic option for cervical leiomyomas with a low rate of surgical complications. Interventional radiology techniques have reported promising but still limited results.

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“…The description of the symptoms was retrievable in 32 studies [ 8 , 17 , 19 , 20 , 21 , 22 , 24 , 25 , 29 , 33 , 34 , 35 , 36 , 37 , 38 , 40 , 41 , 42 , 43 , 44 ] enrolling 130 patients.…”

Section: Resultsmentioning

confidence: 99%

Current Treatment Options for Cervical Leiomyomas: A Systematic Review of Literature

et al. 2021

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“…Лише у 2 жінок у середньому через 43,5 місяця проведена повторна ЕМА через наявність кровопостачання ММ. Пацієнтки були задоволені зменшенням симптомів міоми та покращенням якості життя [99].…”

Section: перешийкові вузлиunclassified

Uterine artery embolization

Plaksiieva¹,

Косей²,

Татарчук³

et al. 2022

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Uterine fibroids (UF) is an extremely common benign tumor of the female reproductive system. This pathology is often associated with symptoms that significantly impair the quality of life of a woman and her working capacity, and can also affect the ability to conceive and gestation. Today, we have in the arsenal of operational, drug and minimally invasive methods of UF treatment. One of the most researched and at the same time rather controversial methods of UF treatment is uterine artery embolization (UAE).Literary sources were reviewed using the MEDLINE, PubMed and Web of Science databases for the period 2011–2021. The data related to the history of the technique development, its implementation, indications and contraindications for UAE, its effect on the UF symptoms and on fertility were systematized and presented in this review.UAE as an independent method for the treatment of benign uterine tumors has 20 years of experience in the world and in Ukraine. The indications for UAE are symptomatic UF: profuse and/or prolonged menstruation, dysmenorrhea, compression of the pelvic organs, dyspareunia, frequent urination or urinary retention. Absolute contraindications for UAE are genital tract infections, pregnancy, doubts about the diagnosis, as well as contraindications to the use of X-ray contrast agents.The effectiveness of UAE is assessed by the manifestations of UF symptoms and by the degree of fibroids size reduction. The average node reduction in the diameter is 2.2 cm. The clinical efficacy index is 81–96, 70–100 and 46–100% respectively in the treatment of abnormal uterine bleeding, pelvic pain and symptoms of compression of adjacent organs. There is a decrease in the node volume by 25–60% within 3–6 months.Conclusions. UAE today is an effective and safe minimally invasive operation, which is a worthy alternative to hysterectomy and expands the possibilities of organ-preserving technologies if there is UF.

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“…Cervical fibroids are extremely rare, accounting for fewer than 5% of uterine myomas, with around 50% being symptomatic [ 1 , 2 ]. They are usually asymptomatic but can cause abnormal uterine bleeding (AUB), chronic pelvic pain, dysmenorrhea, pressure-related symptoms, and infertility [ 3 ]. Conservative therapy options, such as myomectomy, can be considered in patients planning to conceive in the future.…”

Section: Introductionmentioning

confidence: 99%

Spontaneous Expulsion of a Huge Cervical Fibroid After Uterine Artery Embolization Done as a Lifesaving Procedure for Acute Severe Abnormal Uterine Bleeding

Memon¹,

Acharya²,

Potdar³

2022

Cureus

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Uterine fibroids are a prevalent disease that most commonly affects women of reproductive age group and causes symptoms such as abnormal uterine bleeding that can have a detrimental impact on their quality of life. Being in the reproductive age group, fertility-conserving modalities in the form of hormonal therapy, myomectomy, hysterectomy, and uterine artery embolization (UAE) remain the main treatment options. Uterine artery embolization is one of the treatment options for select cases of fibroid uterus. Here, we present the case of a 36-year-old woman diagnosed with cervical leiomyoma who presented with uncontrollable uterine bleeding, severe anemia, and many failed medical therapies. Although the case did not fit within the usual UAE guidelines, the treatment was done to tide over the crisis as a temporary method to control severe hemorrhage. Bleeding was controlled immediately and the patient was getting prepared for major surgery with the correction of severe anemia. However, seven days after UAE, the fibroid spontaneously expelled itself, resulting in improved symptoms and the avoidance of surgery. The patient is currently symptomless and has improved sexual life, self-esteem, and quality of life.

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Uterine Artery Embolization in Women with Symptomatic Cervical Leiomyomata: Efficacy and Safety

Cited by 8 publications

References 23 publications

Current Treatment Options for Cervical Leiomyomas: A Systematic Review of Literature

Current Treatment Options for Cervical Leiomyomas: A Systematic Review of Literature

Uterine artery embolization

Spontaneous Expulsion of a Huge Cervical Fibroid After Uterine Artery Embolization Done as a Lifesaving Procedure for Acute Severe Abnormal Uterine Bleeding

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