UTERINE ARTERY EMBOLIZATION OF SYMPTOMATIC UTERINE FIBROIDS. Initial success and short-term results

Andersen, Poul Erik; Lund, N.; Justesen, Per; Munk, Torben; Elle, Bo; Floridon, Charlotte

doi:10.1034/j.1600-0455.2001.042002234.x

Cited by 22 publications

(14 citation statements)

References 20 publications

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“…The reduction in the dominant fibroid volume in our study was comparable to these studies with a mean volume of 69.4 cm 3 before UFE and 41.4 cm 3 after UAE, which resulted in a 40.1% volume reduction ( P < 001). [ 22 ] Similar observations were also made by Andersen et al,[ 25 ] Spies and colleagues,[ 26 ] and Walker and Pelage,[ 27 ] who reported ranges between 35% and 55%.…”

Section: Discussionsupporting

confidence: 79%

Uterine Fibroid Embolization for Symptomatic Fibroids: Study at a Teaching Hospital in Kenya

Mutai

Vinayak

Stones

et al. 2015

Journal of Clinical Imaging Science

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Objective:Characterization of magnetic (MRI) features in women undergoing uterine fibroid embolization (UFE) and identification of clinical correlates in an African population.Materials and Methods:Patients with symptomatic fibroids who are selected to undergo UFE at the hospital formed the study population. The baseline MRI features, baseline symptom score, short-term imaging outcome, and mid-term symptom scores were analyzed for interval changes. Assessment of potential associations between short-term imaging features and mid-term symptom scores was also done.Results:UFE resulted in statistically significant reduction (P < 0.001) of dominant fibroid, uterine volumes, and reduction of symptom severity scores, which were 43.7%, 40.1%, and 37.8%, respectively. Also, 59% of respondents had more than 10 fibroids. The predominant location of the dominant fibroid was intramural. No statistically significant association was found between clinical and radiological outcome.Conclusion:The response of uterine fibroids to embolization in the African population is not different from the findings reported in other studies from the west. The presence of multiple and large fibroids in this study is consistent with the case mix described in other studies of African-American populations. Patient counseling should emphasize the independence of volume reduction and symptom improvement. Though volume changes are of relevance for the radiologist in understanding the evolution of the condition and identifying potential technical treatment failures, it should not be the main basis of evaluation of treatment success.

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Section: Discussionsupporting

confidence: 79%

Uterine Fibroid Embolization for Symptomatic Fibroids: Study at a Teaching Hospital in Kenya

Mutai

Vinayak

Stones

et al. 2015

Journal of Clinical Imaging Science

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“…Since the first case reports by Ravina, et al, this procedure has been shown to be safe and effective [2,35]. In UAE studies using permanent microspheres as an embolic, fibroid volume decreased by 53.4 ± 26.9%, 3 months after UAE, by 63.7 ± 28.2% after 6 months, and by 71.8 ± 26.8% after 12 months [36,37]. Randomized comparative trials of embolics have shown differences in infarction rate between the different commercial products.…”

Section: Introductionmentioning

confidence: 99%

Polymeric materials for embolic and chemoembolic applications

Poursaid

Jensen

Huo

et al. 2016

Journal of Controlled Release

117

103

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Percutaneous transcatheter embolization procedures involve the selective occlusion of blood vessels. Occlusive agents, referred to as embolics, vary in material characteristics including chemical composition, mechanical properties, and the ability to concurrently deliver drugs. Commercially available polymeric embolics range from gelatin foam to synthetic polymers such as poly(vinyl alcohol). Current systems under investigation include tunable, bioresorbable microspheres composed of chitosan or poly(ethylene glycol) derivatives, in situ gelling liquid embolics with improved safety profiles, and radiopaque embolics that are trackable in vivo. This article reviews commercially available materials used for embolization as well as polymeric materials that are under investigation.

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“…30 We used, on average, two particle flasks, perhaps because of the elasticity of the use of different particle sizes, or because we established technical success when we observed the absence of flow and retention of contrast in the uterus, known as the parenchymatous phase of embolization, an event that sometimes varies from one report to another. 30 From a technical viewpoint, we observed the importance of the gynecologist's participation in the judicious selection of cases, explaining the technique to be adopted for the patient, answering patients' queries and, especially, transmitting security through his presence on the day of the procedure. In addition, the increasing experience and consequent greater skill of the operating radiologist may lead to more rapid embolization procedures, with gradually reduced exposure to radiation.…”

Section: Discussionmentioning

confidence: 99%

Uterine artery embolization for the treatment of symptomatic myomas in Brazilian women

et al. 2003

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The significant reduction in uterine and dominant myoma volume confirms the validity of the treatment of symptomatic myomas by the technique of uterine artery embolization in Brazilian women. There was significant reduction in menstrual flow and duration, as well as better cycle regularity in the women studied. The few adverse effects observed in the sample studied mainly involved pain immediately after embolization.

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UTERINE ARTERY EMBOLIZATION OF SYMPTOMATIC UTERINE FIBROIDS. Initial success and short-term results

Cited by 22 publications

References 20 publications

Uterine Fibroid Embolization for Symptomatic Fibroids: Study at a Teaching Hospital in Kenya

Uterine Fibroid Embolization for Symptomatic Fibroids: Study at a Teaching Hospital in Kenya

Polymeric materials for embolic and chemoembolic applications

Uterine artery embolization for the treatment of symptomatic myomas in Brazilian women

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