Uterine blood flow in sheep and goats during the peri-parturient period assessed by transrectal Doppler sonography

Elmetwally, Mohammed A; Bollwein, Heinrich

doi:10.1016/j.anireprosci.2016.11.005

Cited by 27 publications

(34 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previously gravid uterine horn diameter was measured 7.72 ± 0.3 cm on the day of parturition, and decreased to 1.87 ± 0.1 cm on day 18 postpartum in German Merino ewes [9]. Uterine secretions were gradually decreased within two weeks in the same study.…”

Section: Discussionmentioning

confidence: 54%

“…According to Hauser & Bostedt's [19] findings, 50% of uterine size was rapidly regressed within first 5 days, subsequently the uterine involution was completed by day 17 postpartum. However, 50% reduction of postpartum uterus was also reported by day 9 [9], and by day 14 [2]. The previously gravid horn diameters on day 7 were 3.85 ± 0.15 cm, 3.87 ± 0.20 cm, and 4.42 ± 0.28 cm in Group 1, 2, and 3, respectively (Figure 1).…”

Section: Discussionmentioning

confidence: 80%

“…Color Doppler ultrasonography allows qualitative evaluation of tissue vascularization, direction and velocity of blood flow, whereas pulsed-wave Doppler ultrasonography mode is preferred for quantitative evaluations of tissue hemodynamics via various spectral parameters [11,27,30]. Several studies have been done on pulsedwave Doppler sonographic examinations in sheep reproduction as maternal and/or fetal blood flow characterization during pregnancy [3,4,10,12,36]; and uterine hemodynamics during perinatal-postpartum period [9,22,23,38]. Effects of PGF 2α administration were studied on uterine blood flow by invasive techniques [5,6], and on uterine involution by B-mode ultrasonography [2].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

B-mode and Doppler Ultrasonographic Assessment of Uterine Involution in Ewes Treated with Two Different Doses of ProstaglandinF2α

Dal

Enginler

Çetin

et al. 2020

Acta Scientiae. Vet.

View full text Add to dashboard Cite

Background: Several studies consisted of postmortem evaluations and B-mode ultrasonography have been performed on ovine uterine involution. However, researches with Doppler ultrasonography are very limited in ewes. Doppler ultrasonography is a non-invasive method which provides information about vascular dynamics of the tissues which cannot be examined by B-mode ultrasonography. The aim of the study was to evaluate the effects of two different PGF2α doses on uterine measurements by real time B-mode ultrasonography; and on uterine artery hemodynamics by pulsed-wave Doppler analysis during postpartum uterine involution in ewes.Materials, Methods & Results: The study was conducted with 30 primiparous Kiwircik ewes which lambed singleton without any complication. The ewes were randomly divided into three groups (n= 10 for each group). A single i.m. injection of 125 μg/sheep PGF2α, 75 μg/sheep PGF2α, and 1.0 mL/sheep sterile saline solution were administered to Group 1, 2, and 3, respectively. The day of parturition was considered as the first day of the study. Examinations were performed on days 1, 2, 3, 7, 14, 21 and 28. Diameters of previously gravid horn and caruncles were measured by real time B-mod ultrasonography. Presence of lochia was also noted. Uterine artery pulsatility index (PI), resistance index (RI), systolic/diastolic ratio (S/D) values were measured by pulsed-wave Doppler ultrasonography. The one-way analysis of variance and Duncan’s test were used for statistical analysis. The mean previously gravid horn diameters of ewes were 8.30 ± 0.16 cm and 1.53 ± 0.07 cm on day 1 and day 28, respectively. Previously gravid horn and caruncle diameters had a similar declining pattern in all groups as involution period proceeded. Involution was mostly completed by day 21. More than 50% reduction in uterine size was achieved in prostaglandin administered groups by day 7. Caruncles were not able to be identified after the second week postpartum. Lochia was observed for a longer period in control group. Uterine artery PI and RI showed fluctuations throughout involution period with a similar pattern among groups. S/D values progressively increased until day 14, then showed a decreasing pattern.Discussion: The effects of different PGF2α doses on uterine measurements and uterine artery hemodynamics during postpartum period were compared in ewes for the first time. The uterine size reduction in prostaglandin administered groups suggested that both PGF2α doses were effective in uterine involution. The last observation of lochia in uterine cavity were achieved by day 7 in prostaglandin administered groups, suggesting both PGF2α doses trigger uterine contractions which lead to the removal of uterine content. Automatic measurements by Doppler device were taken in order to provide uniformity and to prevent operator-based bias. The significantly higher uterine artery PI value found in Group 1 on day 1 might suggest the stimulatory effect of PGF2α administration on uterine contractility synergitically with already released endogenous PGF2α. Uterine artery PI and RI showed fluctuations throughout involution period and reached their peak values on day 14. The increasing S/D values up to day 14 indicated increasing diastolic flow, increasing resistance and decreasing blood perfusion in prostaglandin administered groups. Prostaglandin administered groups tended to show higher hemodynamic parameters throughout the study which suggested a vasoconstrictor effect of PGF2α. In conclusion, PGF2α administration on the day of parturition might have constrictor effects both on uterine artery and myometrium which leads to a reduction in uterine blood flow and a rapid decline in uterine size especially during early puerperium even with a reduced dose.

show abstract

Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

B-mode and Doppler Ultrasonographic Assessment of Uterine Involution in Ewes Treated with Two Different Doses of ProstaglandinF2α

Dal

Enginler

Çetin

et al. 2020

Acta Scientiae. Vet.

View full text Add to dashboard Cite

show abstract

“…The serial damages to adenomyosis might have necessitated the obvious change in MRI imaging because we could not see any changes on T2‐weighted imaging during the first attack at 22 weeks. In addition, the post‐partum period is a phase with an acute decrease of uterine blood flow . The rapid decrease of uterine flow in adenomyosis during the post‐partum period might have accelerated the progression of degeneration of adenomyosis, resulting in the clear changes on T2‐weighted imaging.…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging of degeneration of uterine adenomyosis during pregnancy and post‐partum period

Hirashima

Ohkuchi

Usui

et al. 2018

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Degeneration of adenomyosis during pregnancy and the post-partum period is very rare. A 42-year-old Japanese parous woman with four normal-term deliveries, who presented with abdominal pain and fever at 22 weeks of gestation with transient increases of the white blood cell count and C-reactive protein, demonstrated sustained inflammation after cesarean section at 29 weeks of gestation due to the occurrence of gestational hypertension with late deceleration. The noncontrast-enhanced magnetic resonance imaging (MRI) at 22 weeks demonstrated a poorly demarcated hypointense area at the posterior uterine wall on T1- and T2-weighted imaging. The 2nd MRI 2 weeks after the cesarean section showed hypointensity on a T1-weighted image and hyperintensity on a T2-weighted image, allowing confirmation of the diagnosis of degeneration of adenomyosis. Repeated MRIs were clinically useful to diagnose the degeneration of adenomyosis.

show abstract

“…The restoration of the uterus to its normal non-pregnant size and function after parturition is termed uterine involution which depends on the rate of myometrial contractions, elimination of bacterial infection and the histological regeneration of the endometrium [1,2,3]. Involution of the uterus is necessary before the cow can conceive again.…”

Section: Uterine Involutionmentioning

confidence: 99%

Uterine Involution and Ovarian Activity in Postpartum Holstein Dairy Cows. A Review

Elmetwally

2018

JVHC

View full text Add to dashboard Cite

Following parturition in the cow, there is a significant period of sexual quiescence of variable length. This period of reproductive quiescence was found to be longer in suckling or intensively milked animals.This acyclic period is generally considered as the postpartum anoestrous period. The postpartum period constitutes an important period in the reproductive life of dairy cows because of its enormous influence upon subsequent fertility. The entire postpartum period, puerperium, is defined as the period from parturition until the genital organs return to its normal physiological and histological condition, as in normal non-gravid state. They added that any extension of the puerperium in cows might have a detrimental effect on the reproductive performance of the individual animal. Thus, the main determinant of this period is essentially dependent on the resumption of normal ovarian cycles, the manifestation of estrus behaviour and conception following insemination.

show abstract

Uterine blood flow in sheep and goats during the peri-parturient period assessed by transrectal Doppler sonography

Cited by 27 publications

References 16 publications

B-mode and Doppler Ultrasonographic Assessment of Uterine Involution in Ewes Treated with Two Different Doses of ProstaglandinF2α

B-mode and Doppler Ultrasonographic Assessment of Uterine Involution in Ewes Treated with Two Different Doses of ProstaglandinF2α

Magnetic resonance imaging of degeneration of uterine adenomyosis during pregnancy and post‐partum period

Uterine Involution and Ovarian Activity in Postpartum Holstein Dairy Cows. A Review

Contact Info

Product

Resources

About