Uterine Cervical Metastasis From Primary Rectal Adenocarcinoma on PET/CT and MRI

Abstract

FDG avid uterine cervical masses are most commonly due to primary cervical carcinoma; however, history and differential diagnoses are critical when interpreting FDG PET/CT studies. A 51-year-old woman with newly diagnosed moderately differentiated adenocarcinoma of the rectum underwent FDG PET/CT for staging, which revealed the hypermetabolic primary rectal tumor and nodal metastases. Additionally, FDG avid focus in the anterior cervix without a CT correlate was present. Cervical metastasis was suspected, and further evaluation with MRI and histopathologic correlation was recommended, which confirmed cervical metastasis. This case illustrates an unusual case of FDG-avid cervical metastasis from rectal adenocarcinoma.

Solitary Abdominal Wall Metastasis From Rectal Carcinoma Revealed on FDG PET/CT

“…The final pathology supported a diagnosis of metastasis from rectal carcinoma. Rare distant metastasis sites of colorectal cancer include tonsil, 1 kidney, 2 vagina, 3,4 uterus, 5,6 thigh muscle, 7 and thyroid 8 . However, solitary abdominal wall metastasis from rectal adenocarcinoma is very rare.…”

Ovarian Inflammation Mass Mimicking Recurrent Rectal Cancer 17 Years After Surgery

“…It is reported that FDG PET/CT was helpful in detecting local recurrence, especially extraluminal recurrence of rectal cancer 1–3 . Several cases have reported PET/CT findings of rare metastatic/recurrent pelvic sites from rectal cancer including vagina, 4 uterine, 5,6 and penile, 7 which were hypermetabolic masses with SUVmax ranging from 7.4 to 11. In addition to malignant metastases, active inflammation may also result in high glucose metabolism 8 .…”