2008
DOI: 10.1517/14728214.13.1.119
|View full text |Cite
|
Sign up to set email alerts
|

Uterine myoma: a condition amendable to medical therapy?

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
26
0
4

Year Published

2010
2010
2022
2022

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 56 publications
(30 citation statements)
references
References 156 publications
0
26
0
4
Order By: Relevance
“…Owing to the multitude of factors involved in leiomyoma pathogenesis, attempts to target a single pathway have not attained satisfactory results. The simultaneous targeting of several pathways and signaling intermediates situated downstream and analysis of specific proteins expression patterns would be beneficial in the elucidation of signaling cascades leading to the formation and the progression of leiomyomas, as well as in the development of more effective treatments for this disease (3).…”
mentioning
confidence: 99%
“…Owing to the multitude of factors involved in leiomyoma pathogenesis, attempts to target a single pathway have not attained satisfactory results. The simultaneous targeting of several pathways and signaling intermediates situated downstream and analysis of specific proteins expression patterns would be beneficial in the elucidation of signaling cascades leading to the formation and the progression of leiomyomas, as well as in the development of more effective treatments for this disease (3).…”
mentioning
confidence: 99%
“…Üreme çağındaki kadınlarda en sık görülen bening tümor olan myomların %80'i asemptomatiktir (6). Cerrahi tedavi seçenekleri semptomlarla ilişkili olarak, endometriyal ablasyon, abdominal, laparoskopik, vajinal myomektomi veya histerektomiyi içerir.…”
Section: Discussionunclassified
“…Also, HDL cholesterol decreased significantly in the progestin add-back group, an effect that was not seen in the combination group [27]. [5,21]. In one study, ganirelix induced 42.7% shrinkage in uterine fibroids with a median treatment duration of 19 days [28].…”
Section: Gnrha With Combined Estrogen and Progesteronementioning
confidence: 98%
“…Aromatase is needed to convert androstenedione to estrone and testosterone to estradiol [21]. Aromatase mRNA is expressed in myoma but is not expressed in normal myometrial cells [30,31].…”
Section: Aromatase Inhibitorsmentioning
confidence: 99%
See 1 more Smart Citation