Uterine Sarcomas: Surgical Management, Adjuvant Therapy and Survival Outcome. Experience at Gujarat Cancer and Research Institute

Patel, Shilpa M.; Tiwari, Rajnish; Arora, Ruchi; Poddar, Pabashi; Desai, Ajesh; Mankad, Meeta

doi:10.1007/s40944-018-0247-0

Cited by 2 publications

(3 citation statements)

References 27 publications

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“…Surgical intervention is the treatment of choice with Total abdominal hysterectomy, bilateral salpingo -oophorectomy for postmenopausal females and those with metastatic disease and Total abdominal hysterectomy without bilateral salphingo -oophorectomy for premenopausal females. 5 Hormonal therapy may be an option in hormone receptor positive tumors.…”

Section: Discussionmentioning

confidence: 99%

“…Whereas cellular leiomyomas and leiomyosarcomas are usually positive for CD10 and positive for desmin, immunohistochemistry can be helpful in difficult cases. 4,5 Carcinosarcoma was also a differential diagnosis as they commonly present as a uterine polyp in post menopausal women. But in our case, there was absence features of endometrioid, serous or clear cell type adenocarcinoma.…”

Section: The Ihc Profile Of This Casementioning

confidence: 99%

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Immunohistochemical markers in differential diagnosis of endometrial stromal sarcoma and leiomyosarcoma in an endometrial polyp: A case report

Hawaldar¹,

Khan²,

Patidar³

2023

ACHR

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Leiomyosarcoma is the malignant counterpart of leiomyoma. It arises from smooth muscle of the uterus and is rare tumor that account for 2-5% of all uterine malignancy. We report a case of 60 years old female who presented with post menopausal bleeding with endometrial polyp. A total abdominal hysterectomy specimen was received in our center. A differential diagnosis of leiomyosarcoma/ Endometrial stromal sarcoma was made by histopathological examination. Immunohistochemistry report confirmed the diagnosis of uterine Leiomyosarcoma.

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Section: Discussionmentioning

confidence: 99%

Section: The Ihc Profile Of This Casementioning

confidence: 99%

Immunohistochemical markers in differential diagnosis of endometrial stromal sarcoma and leiomyosarcoma in an endometrial polyp: A case report

Hawaldar¹,

Khan²,

Patidar³

2023

ACHR

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show abstract

“…Approximately 1 in every 800 women believed to have a leiomyoma actually has a sarcoma 6,7. Though uterine sarcoma is very rare, it usually causes poor prognosis 8. However, preoperative examination, either imaging with ultrasonography or with positron emission tomography scans, is not capable to differentiate benign from malignant smooth muscle masses.…”

Section: Introductionmentioning

confidence: 99%

<p>A Case Report Of Uterine Leiomyosarcoma</p>

Cao¹,

Liu²,

Bai³

et al. 2019

OTT

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BackgroundUterine leiomyoma is the most common benign tumor in women. Uterine sarcoma, though with very low incidence, has a high malignant degree and poor prognosis. It has difficulties in preoperative diagnosis, frozen pathological examination and postoperative treatment.Case reportA 49-year-old woman presented with menstrual disorder. Magnetic resonance imaging showed a huge uterine mass. The patient underwent laparoscopic hysterectomy and part of the uterine tissue looked like fish. Specimens were sent to frozen pathological examination for four times, but none of the results showed malignancy certainly. Considering all abnormalities, we removed the uterine through vagina completely rather than morcellation and did pelvic lymph node biopsy. Postoperative pathological examination revealed uterine leiomyosarcoma and one pelvic lymph node had metastasized.ConclusionUterine sarcoma is difficult to be diagnosed even frozen pathological examination has been performed. Unexpected uterine sarcoma should always be considered, and precautions should be taken if we find anything suspicious. Fortunately, the patient has avoided second operation.

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Uterine Sarcomas: Surgical Management, Adjuvant Therapy and Survival Outcome. Experience at Gujarat Cancer and Research Institute

Cited by 2 publications

References 27 publications

Immunohistochemical markers in differential diagnosis of endometrial stromal sarcoma and leiomyosarcoma in an endometrial polyp: A case report

Immunohistochemical markers in differential diagnosis of endometrial stromal sarcoma and leiomyosarcoma in an endometrial polyp: A case report

<p>A Case Report Of Uterine Leiomyosarcoma</p>

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