Uterine transplantation in transgender women: medical, legal and ethical considerations

Hammond-Browning, Natasha

doi:10.1111/1471-0528.15482

Cited by 13 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hence, male‐to‐female transgender women are legally entitled to the same treatment as women assigned female at birth, should it be feasible. However, ongoing debate related to the Human Fertilisation and Embryology Act 2008, highlights the potential legal implications of performing embryo transfer in transgender women, which would be necessary following UTx. Moreover, a number of complicating factors exist, including the lack of physiologically functioning vaginal mucosa, differing pelvic size, and shape and hormonal variation, which raise uncertainty regarding the feasibility in this model …”

Section: Recipientsmentioning

confidence: 99%

Human uterine transplantation: a review of outcomes from the first 45 cases

Jones

Saso

Bracewell‐Milnes

et al. 2019

BJOG

142

195

View full text Add to dashboard Cite

Uterine transplantation restores reproductive anatomy in women with absolute uterine factor infertility and allows the opportunity to conceive, experience gestation, and acquire motherhood. The number of cases being performed is increasing exponentially, with detailed outcomes from 45 cases, including nine live births, now available. In light of the data presented herein, including detailed surgical, immunosuppressive and obstetric outcomes, the feasibility of uterine transplantation is now difficult to refute. However, it is associated with significant risk with more than one-quarter of grafts removed because of complications, and one in ten donors suffering complications requiring surgical repair.Tweetable abstract Uterine transplantation is feasible in women with uterine factor infertility, but is associated with significant risk of complication.

show abstract

Section: Recipientsmentioning

confidence: 99%

Human uterine transplantation: a review of outcomes from the first 45 cases

Jones

Saso

Bracewell‐Milnes

et al. 2019

BJOG

142

195

View full text Add to dashboard Cite

show abstract

“…I thank you for the opportunity to respond to the letter submitted in response to my mini‐commentary on uterine transplantation in transgender women . I agree with Jones, Alghrani and Smith that current legislation is not well equipped to govern the rapidly developing field of uterus transplantation (UTx).…”

Section: Disclosure Of Interestsmentioning

confidence: 95%

Author's reply re: Uterine transplantation in transgender women: medical, legal and ethical considerations

Hammond-Browning

2018

BJOG

View full text Add to dashboard Cite

“…Therefore, although the first clinical UTx was in 2000, the first baby born after successful UTx was in Sweden in 2014 [2]. Inspired by this success, approximately 42 UTx procedures have now been reported globally, and at least 12 live births have been reported in recent years [3]. The improved outcome increases the number of such cases which challenges the anesthesia team.…”

Section: History Of Uterine Transplantmentioning

confidence: 99%

Anesthetic Considerations for Cesarean Delivery After Uterine Transplant

Shehata¹,

Barsoumv²,

Elhass³

et al. 2021

Cureus

View full text Add to dashboard Cite

Infertility has many etiologies and can have devastating consequences for young couples attempting to bring children into the world. Uterine factor for infertility is related to either uterine agenesis (Mayer-Rokitansky-Küster-Hauser [MRKH] syndrome), unexpected hysterectomy, or presence of a nonfunctioning uterus. In this review, a patient with MRKH syndrome underwent donor uterus transplantation at the Cleveland Clinic, conceived, and delivered the first healthy baby in the United States and the second worldwide. Additionally, we review the pertinent literature on anesthesia problems. Donor-related uterine transplant is a recent medical innovation requiring multidisciplinary expertise. In patients who deliver successfully, according to the current literature, the transplanted uterus can be used for one more pregnancy only if the mother so desires, otherwise cesarean hysterectomy (C-Hyst) should be performed. In the observed case, C-Hyst was performed because the patient developed placenta accreta and the couple desired no further pregnancy. In summary, with our limited data, careful management of these patients is required to ensure the best outcome for the mother and the newborn fetus.

show abstract

Uterine transplantation in transgender women: medical, legal and ethical considerations

Cited by 13 publications

References 0 publications

Human uterine transplantation: a review of outcomes from the first 45 cases

Human uterine transplantation: a review of outcomes from the first 45 cases

Author's reply re: Uterine transplantation in transgender women: medical, legal and ethical considerations

Anesthetic Considerations for Cesarean Delivery After Uterine Transplant

Contact Info

Product

Resources

About