Uterine Tumors Resembling Ovarian Sex Cord Tumors – Treatment, recurrence, pregnancy and brief review

Abstract

BackgroundUterine Tumors Resembling Ovarian Sex Cord Tumors (UTROSCT) are rare tumors of low malignancy. In the past, these tumors were mainly treated by hysterectomy. More recently, some authors have proposed conservative surgical management for women wishing to preserve fertility. This article is the first to report on organ-preserving treatment in the case of recurrence or disease persistence.CasesWe report on three patients with UTROSCT, two of them young, not having completed family planning. One even gave birth to a healthy child after fertility-preserving treatment of a persistent UTROSCT. To our knowledge, this is the first pregnancy reported after surgical treatment of a persistent UTROSCT so far.ConclusionA fertility-sparing approach should always be considered in young women with UTROSCT who wish to preserve their fertility, also in cases of recurrence or disease persistence.

Uterine Tumor Resembling Ovarian Sex Cord Tumors Type II with Vaginal Vault Recurrence

“…To date, less than 100 cases of UTROSCT have been reported [4]. Although the typical behavior of UTROSCT is benign, metastatic and recurrent cases could occur [5].…”

A Case of Uterine Tumor Resembling Ovarian Sex Cord Tumor Treated With Uterine Wedge Resection

“…Fertility sparing surgery for young patients had been reported by some authors (2,3,5,6). Most of them are done by resectoscope and some by abdominal myomectomy.…”

“…Hysterectomy with or without adnexectomy is the preferred choice of treatment. Fertility preserving treatment options are seen more commonly in the last decade for young patients since these tumors have low malignant potential (2). Hysteroscopic resection of the tumor is the most frequent approach.…”

Ectopic hyperprolactinaemia due to a malignant uterine tumor resembling ovarian sex cord tumors (UTROCST)

“…Patients with UTROSCT typically present with metrorrhagia and/or a uterine mass [ 8 , 36 ]. This category of uterine neoplasms with variable biological behaviour is divided into two groups: uterine tumors resembling ovarian sex cord tumors (UTROSCT), and the related endometrial stromal tumors with sex cord-like elements (ESTSCLE) [ 37 ]. According to World Health Organisation (WHO), UTROSCT is currently defined as the “neoplasm resembling ovarian sex cord tumors without a component of recognizable endometrial stroma” (WHO, I.A.R.C.…”