Uterine Ultrasound Doppler Hemodynamics of Magnesium Sulfate Combined with Labetalol in the Treatment of Pregnancy-Induced Hypertension Using Empirical Wavelet Transform Algorithm

Abstract

The aim of this study was to explore the hemodynamic changes of magnesium sulfate combined with labetalol in the treatment of pregnancy-induced hypertension (PIH) under Doppler uterine ultrasound based on the empirical wavelet transform (EWT) algorithm. 500 patients with PIH in the hospital were selected and randomly divided into the control group (n = 250) and the observation group (n = 250). The control group was treated with conventional magnesium sulfate; the observation group was given labetalol based on magnesium sulfate drip in the control group. The uterine artery blood flow simulation model was established based on the EWT algorithm and compared with a short-time Fourier transform (STFT). The normalized root mean square error (NRMSE) of the STFT method was 0.19, and the NRMSE extracted by the EWT method was 0.13. After treatment, the blood pressure index, 24-hour urinary protein, and incidence of adverse birth outcomes in the observation group were lower than those in the control group; the effective rate of the control group (90.4%) was lower than that of the observation group (97.6%); the hemodynamic indexes of the uterine artery in the observation group were lower than those in the control group, and the differences were statistically significant ( P < 0.05 ). The estimation accuracy of the EWT method was higher than that of the traditional STFT method; the combined treatment of magnesium sulfate and labetalol in patients with PIH had a remarkable effect, which could control the blood pressure index and reduce the 24-hour urinary protein; the uterine artery Doppler ultrasound examination could change hemodynamics and improve the adverse outcomes of mothers and infants.

Application of Acupoint Catgut Embedding Therapy Combined with Liuzijue Breathing Exercise in the Treatment of Patients with Stable Chronic Obstructive Pulmonary Disease

“…Results showed a significantly higher treatment effective rate and a remarkably lower number of acute exacerbations, which indicates the promising performance of the combination of the two therapies. Scholar Siqin et al performed Liuzijue breathing exercises and acupoint massage for patients with stable COPD and confirmed that the ADL score of the experimental group after treatment was (69.68 ± 2.31) points, and the QOL score was (50.11 ± 2.10) points, both of which were significantly better than those of the control group (P < 0.05) [22,23], suggesting the advantages of long-term and specific effects of acupoint therapy on COPD. Moreover, the body's response to traditional Chinese medicine therapy is rather mild, which has been proven by the absence of serious adverse reactions during the treatment.…”

Pharmaceutical administration for severe hypertension during pregnancy: Network meta-analysis

“…Diuretics are the mainstay of treatment for non-gestational hypertension because they theoretically act on plasma volume depletion to cause reactive vasoconstriction, but in some earlier studies, diuretics were found to be safe during pregnancy ( Garovic et al, 2022 ). Guidelines from the Multidisciplinary Working Group of the National Organization for Safe Motherhood advocated that reduced the use of magnesium sulfate as a quasi-first-line antihypertensive agent ( Liu et al, 2022 ; Yu and Zhou, 2022 ). Studies suggested that the exclusive treatment of magnesium sulfate to treat pregnancy-induced hypertension (PIH) will affect fetal development ( Pascoal et al, 2019 ).…”