2020
DOI: 10.24018/ejchem.2020.1.6.29
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Utility Of 6-Azauracils In Synthesis of New Poly Heterocyclic Nitrogen Systems Bearing 1,2,4-Triazine Moiety as Antioxidant Probes.

Abstract: Synthesis of new poly heterocyclic nitrogen systems containing 1,2,4-triazine moiety such as pyrazolines, pyrazolones, phthalazinone and 1,2,4-triazinone (9-17) have been deduced from hydrazinolysis of 3,5-dichloro-6,1-dihydro-1,2,4-triazine (2) which produced from the interaction between 6-azauracil (1) with POCl3/PCl5. Heterocyclization of 3,5-dihydrazino-1,2,4-triazine (7) by reaction nitrogen / oxygen / halogen bifunctional reagents in different mediums and conditions yielded the targets 9-17 respectively.… Show more

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