Utility of autologous fibrin glue in the donor site of free abdominal flap for breast reconstruction: A randomized controlled study

Tokumoto, Hideki; Akita, Shinsuke; Kubota, Yoshitaka; Mitsukawa, Nobuyuki

doi:10.1016/j.bjps.2021.03.073

Cited by 7 publications

(2 citation statements)

References 37 publications

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“…Three retrospective non-randomised studies with controls reported donor site complications (Additional file 2 ) [ 45 , 54 , 63 ]. One of the studies [ 55 ] reported that there were zero donor site complications, whereas the other [ 45 ] stated that the rate of abdominal seromas requiring drainage was higher in the group where the SIEV had been harvested, especially if it had been harvested bilaterally.…”

Section: Resultsmentioning

confidence: 99%

A systematic review of the scientific evidence of venous supercharging in autologous breast reconstruction with abdominally based flaps

Hansson,

Ramakrishnan,

Morgan

2023

World J Surg Onc

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Background Abdominally based free flaps are commonly used in breast reconstruction. A frequent complication is venous congestion, which might contribute to around 40% of flap failures. One way to deal with it is venous supercharging. The primary aim of this study was to investigate the scientific evidence for the effects of venous supercharging. Methods A systematic literature search was conducted in PubMed, CINAHL, Embase, and Cochrane library. The included articles were critically appraised, and certainty of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. Results Thirty-six studies were included. Most studies had serious study limitations and problems with directness. Three studies report ‘routine’ use of venous supercharging and performed it prophylactically in patients who did not have clinical signs of venous congestion. Seventeen studies report on flap complications, of which one is a randomised controlled trial demonstrating statistically significant lower complication rates in the intervention group. The overall certainty of evidence for the effect of a venous supercharging on flap complications, length of hospital stay and operative time, in patients without clinical signs of venous congestion, is very low (GRADE ⊕ ⊕ ⊝ ⊝), and low on and surgical takebacks (GRADE ⊕ ⊕ ⊝ ⊝). Twenty-one studies presented data on strategies and overall certainty of evidence for using radiological findings, preoperative measurements, and clinical risk factors to make decisions on venous supercharging is very low (GRADE ⊕ ⊝ ⊝ ⊝). Conclusion There is little scientific evidence for how to predict in which cases, without clinical signs of venous congestion, venous supercharging should be performed. The complication rate might be lower in patients in which a prophylactic venous anastomosis has been performed. Trial registration PROSPERO (CRD42022353591).

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Section: Resultsmentioning

confidence: 99%

A systematic review of the scientific evidence of venous supercharging in autologous breast reconstruction with abdominally based flaps

Hansson,

Ramakrishnan,

Morgan

2023

World J Surg Onc

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“…• Different techniques for dissection /electrocautery [66][67][68] • Different techniques for fat transfer [69] Donor site management • Different regimes for abdominal closure after abdominally based flap [70][71][72][73][74][75][76][77] • Different regimes for back closure after latissimus dorsi harvest [78][79][80][81][82]…”

Section: Surgical Details Valid For Several Categories Of Breast Reco...mentioning

confidence: 99%

A systematic review of randomised controlled trials in breast reconstruction

Hansson,

Larsson,

Uusimäki

et al. 2024

JPHS

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Background: For preference sensitive treatments, such as breast reconstructions, there are barriers to conducting randomised controlled trials (RCTs). The primary aims of this systematic review were to investigate what type of research questions are explored by RCTs in breast reconstruction, where have they been performed and where have they been published, and to thematise the research questions and thus create an overview of the state of the research field. Methods: Randomised controlled trials investigating any aspect of breast reconstructions were included. The PubMed database was searched with a pre-defined search string. Inclusion and data abstraction was performed in a pre-defined standardised fashion. For the purpose of this study, we defined key issues as comparison of categories of breast reconstruction and comparison of immediate and delayed breast reconstruction, when the thematisation was done. Results: A total of 419 abstracts were retrieved from the search. Of the 419, 310 were excluded as they were not RCTs concerning some aspect of breast reconstruction, which left us with 110 abstracts to be included in the study. The research questions of the included studies could more or less be divided into seven different themes inclusive of 2 key issues: Other issues – comparison of different categories of breast reconstruction, comparison of immediate and delayed breast reconstruction, surgical details within a category of breast reconstruction, surgical details valid for several categories of breast reconstruction, donor site management, anaesthetics, and non-surgical details. Only five studies compared key issues, and they all illustrate the challenges with RCTs in breast reconstruction. Conclusions: A total of 110 publications based on RCTs in breast reconstruction have been published. Seven themes of research questions could be identified. Only five studies have explored the key issues. Better scientific evidence is needed for the key issues in breast reconstruction, for example by implementing a new study design in the field.

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Utilization of a partial rib-sparing procedure in microvascular breast reconstruction for preserving intercostal nerve and nipple reconstruction

Tokumoto

Akita²,

Kosaka³

et al. 2022

Journal of Plastic, Reconstructive & Aesthetic Surgery

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Utility of autologous fibrin glue in the donor site of free abdominal flap for breast reconstruction: A randomized controlled study

Cited by 7 publications

References 37 publications

A systematic review of the scientific evidence of venous supercharging in autologous breast reconstruction with abdominally based flaps

A systematic review of the scientific evidence of venous supercharging in autologous breast reconstruction with abdominally based flaps

A systematic review of randomised controlled trials in breast reconstruction

Utilization of a partial rib-sparing procedure in microvascular breast reconstruction for preserving intercostal nerve and nipple reconstruction

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