2021
DOI: 10.3389/fvets.2021.732133
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Utility of Computed Tomographic Angiography for Pulmonary Hypertension Assessment in a Cohort of West Highland White Terriers With or Without Canine Idiopathic Pulmonary Fibrosis

Abstract: West Highland white terriers (WHWTs) affected with canine idiopathic pulmonary fibrosis (CIPF) are at risk of developing precapillary pulmonary hypertension (PH). In humans, thoracic computed tomography angiography (CTA) is commonly used to diagnose and monitor patients with lower airway diseases. In such patients, CTA helps to identify comorbidities, such as PH, that could negatively impact prognosis. Diameter of the pulmonary trunk (PT), pulmonary trunk-to-aorta ratio (PT/Ao), and right ventricle-to-left ven… Show more

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Cited by 1 publication
(7 citation statements)
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References 58 publications
(113 reference statements)
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“…In this study, unlike the RPAD index, the PT:Ao ratio did not show significant differences between healthy dogs and dogs with heartworm without hypertension or mild PH. These results are similar to those reported in previous investigations, which showed a high degree of overlap between PT:Ao ratios of the non-PH and mild-PH groups [ 9 , 10 , 11 ].…”
Section: Discussionsupporting
confidence: 92%
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“…In this study, unlike the RPAD index, the PT:Ao ratio did not show significant differences between healthy dogs and dogs with heartworm without hypertension or mild PH. These results are similar to those reported in previous investigations, which showed a high degree of overlap between PT:Ao ratios of the non-PH and mild-PH groups [ 9 , 10 , 11 ].…”
Section: Discussionsupporting
confidence: 92%
“…The cut-off point to diagnose moderate or severe PH reported for PT:DAo in this study (≥1.111) was slightly lower than previously reported by other authors (> 1.4) in dogs with PH of undescribed etiology [ 10 ]. Moreover, the mean PT:AAo and PT:DAo obtained for healthy dogs were slightly lower than the values presented in previous studies (1.11 ± 0.15 and 0.97 ± 0.12 for PT:AAo, and 1.26 ± 0.11 for PT:DAo) [ 9 , 10 , 11 ]. These differences could be due to the different methodologies established to determine the presence or absence of PH in the studies mentioned.…”
Section: Discussioncontrasting
confidence: 77%
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