Utility of Doppler sonography for renal artery stenosis screening in obese children with hypertension

Makhija, Pooja; Wilson, Christopher L.; Garimella, Sudha

doi:10.1111/jch.13241

Cited by 7 publications

(1 citation statement)

References 29 publications

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“…Therefore, the clinical application of CTA and MRA is limited in some particular cases. Although DUS has been widely used as an initial imaging modality for the diagnosis of renal artery stenosis [ 21 , 22 ], factors such as depth, obesity, complex anatomy, bowl gas, and operator dependent may limit the use of the Doppler ultrasound [ 23 ]. More recently, the use of CEUS in the detection of renal artery stenosis has raised the attention of many researchers [ 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

The Value of Contrast-Enhanced Ultrasound versus Doppler Ultrasound in Grading Renal Artery Stenosis

Cui

Zhang

Yan

et al. 2020

BioMed Research International

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Objective. This study is aimed at exploring the accuracy of contrast-enhanced ultrasound (CEUS) in grading renal artery stenosis. Methods. 122 renal arteries with suspected renal artery stenosis were selected. DSA, DUS, and CEUS were performed for all patients with suspected renal artery stenosis in the research. DSA was selected as the gold standard. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of CEUS or Doppler ultrasound (DUS) in the diagnosis of renal artery stenosis were analyzed. The consistency between CEUS and digital subtraction angiography (DSA) was compared. The accuracy of DUS or CEUS in grading renal artery stenosis was assessed by the area under the receiver operating characteristic (ROC) curves and compared between groups. Results. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CEUS in the diagnosis of renal artery stenosis were 88.9%, 87.8%, 88.5%, 93.5%, and 80.0%, respectively. There was no significant difference in grading renal artery stenosis between CEUS and DSA (X2=0.643, P=0.424). 77 of the 122 renal arteries were diagnosed with the stenosis rate more than 30% by CEUS. Compared with the results of DSA, the kappa value of CEUS was 0.749 (P<0.05). Conclusion. CEUS is accurate in grading renal artery stenosis, and it may represent the method of choice in diagnosing renal artery stenosis.

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