Utility of EUS in the evaluation of cystic pancreatic lesions

Sedlack, Robert E.; Affi, Aboud; Vázquez-Sequeiros, Enrique; Norton, Ian D.; Clain, Jonathan E.; Wiersema, Maurits J.

doi:10.1067/mge.2002.128106

Cited by 88 publications

(113 citation statements)

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“…For larger tumors, even with an excellent positive predictive value, the negative predictive value was lower than 55%. Furthermore, the negative predictive value and diagnostic accuracy of EUS-FNA for cystic lesions were higher than 90%, which are consistent with other studies [29,30] . EUS-FNA has the following advantages over CT-or US-guided FNA: the shorter distance between the gut wall and tumor, the real time visualization of the needle, and the Doppler scanning to avoid punctures of the adjacent blood vessels [10,11] .…”

Section: Discussionsupporting

confidence: 92%

Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration

Ardengh¹,

Lopes²,

Lima³

et al. 2007

WJG

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AIM:To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. For cystic lesions, the values were, respectively, 72.2%, 99.3%, 97.5%, 91% and 92.2%. METHODS:CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions can reveal the best negative predictive value and diagnostic accuracy, both higher than 90%.

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Section: Discussionsupporting

confidence: 92%

Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration

Ardengh¹,

Lopes²,

Lima³

et al. 2007

WJG

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“…Sedlack et al in a retrospective study of 111 patients at Mayo Clinic found that cytology had 100% specificity and 27% sensitivity for mucinous cysts. This translates into 55% diagnostic accuracy [40]. Similar results were confirmed by Attasaranya et al from Indiana University in a retrospective study of 48 patients with pancreatic cysts.…”

Section: Cytological Evaluationsupporting

confidence: 71%

“…Main duct IPMN appears as a cystic dilation of the main pancreatic duct and it could be either segmental or diffuse in nature. EUS can also identify features that are worrisome for malignancy such as solid component, thick septae or lymphadenopathy [40,41]. However, EUS alone cannot differentiate benign from malignant cysts [42].…”

Section: Cyst Morphologymentioning

confidence: 99%

Endoscopic Ultrasonography in Management of Cystic Disease of the Pancreas

Othman¹,

Patel²,

Raimondo³

2011

New Techniques in Gastrointestinal Endoscopy

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“…EUS can be considered complementary for distinguishing such lesions. 19,20 US-FNA sampling of cystic fluid distinguishes mucinous from non-mucinous cysts with high specificity by measurement of cyst fluid CEA levels but does not predict malignancy. 21 However, when ERCP does not visualize a part of the pancreatic duct or common bile duct, this area is usually seen well on EUS.…”

Section: Interventional Eus Proceduresmentioning

confidence: 99%