Utility of FDG-PET for Staging in a Case of Mycosis Fungoides

Borella, Linda; Lin, Michael; Cains, Geoffrey; Watson, Anne-Marie; Lin, Peter

doi:10.1159/000098582

Cited by 6 publications

(4 citation statements)

References 8 publications

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“…Significant morbidity was observed in > 25% following excisional LN biopsy. Use of image‐guided core needle biopsy for CTCL staging has been reported, and the role of fluoro‐2‐deoxy‐D‐glucose positive emission tomography in reducing the need for LN biopsy has been suggested . Additionally, the Prospective Cutaneous Lymphoma International Prognostic Index study (PROCLIPI) of early‐stage MF records size and sites of lymphadenopathy, and provide data on long‐term outcome of enlarged LNs.…”

Section: Thirty‐one Incidental Findings Seen In 29 Patients Across 24mentioning

confidence: 99%

Computed tomography scanning in mycosis fungoides: optimizing the balance between benefit and harm

et al. 2017

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Section: Thirty‐one Incidental Findings Seen In 29 Patients Across 24mentioning

confidence: 99%

Computed tomography scanning in mycosis fungoides: optimizing the balance between benefit and harm

et al. 2017

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“…[3] Only few case reports and investigations assess the potential role of PET/CT in diagnosing and staging primary cutaneous lymphomas including MF. [4] Flurodeoxyglucose (FDG) is the most commonly used positron tracer at present, and its uptake in the malignant tumor is increasing evidently. The lesions in the early stage of MF absorb FDG slightly.…”

Section: Introductionmentioning

confidence: 99%

Mycosis fungoides staged by 18F-flurodeoxyglucose positron emission tomography/computed tomography

Xu¹,

Hua²,

Jin³

et al. 2016

Medicine

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Introduction:Mycosis fungoides is a kind of malignant lymphoma arising from T cells, but primarily occurs in skin, and it is the most common type of cutaneous lymphoma. Mycosis fungoides (MF) is a rare non-Hodgkin lymphoma but the most common type of primary cutaneous T-cell lymphomas. Because of unknown etiology and mechanism, and lack of typical clinical and histophysiological manifestations, the final diagnosis of MF is currently dependent on pathology and immunohistochemistry. Subsequently, tumor staging is very important. Different approaches would be taken according to varying degrees of cutaneous and extracutaneous lesions. Computed tomography (CT) scan has been chosen to stage tumors customarily. However, CT could only provide morphological information and analyze lymphadenopathy by the size criteria. 18F-flurodeoxyglucose positron emission tomography/computed tomography (PET/CT) could provide morphological information and metabolic conditions simultaneously, which is helpful to locate and stage lesion.Conclusion:18F-flurodeoxyglucose PET/CT could identify cutaneous and extracutaneous lesions in patients with MF. It could provide the range of lesions and biopsy target.

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“…[ 4 ] Only few study and case reports evaluate the potential role of PET-CT in diagnosing primary cutaneous lymphomas and specifically MF. [ 5 ] Our study assessed the role of F18 FDG PETCT in patients with MF. We also evaluate the clinical usefulness and suitability of 18 F-FDG PET-CT in MF patients that have risk of secondary LN involvement.…”

Section: Introductionmentioning

confidence: 99%

The role of fluorine-18 fluorodeoxyglucose positron emission tomography in patients with mycosis fungoides

et al. 2015

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Purpose:The aim of the present study is to evaluate the possible role of fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT) in the management of mycosis fungoides (MF).Materials and Methods:Nineteen patients (mean age, 40.6 years; median age 41 years; 16 males and 3 females) with risk of secondary lymph node (LN) involvement (those with large cell transformation, tumors, erythroderma, or enlarged LNs on physical examination) were included in the study. All patients underwent PET-CT scan by injecting 0.06 mCi/kg of F18 FDG. The maximum standard uptake value (SUVmax) was recorded for each patient.Results:The 18F-FDG PET-CT was positive in 15 patients. PET-CT detected local cutaneous disease in 13 cases. The range of SUVmax is 2.8–14.1. Out of 19 patients, hypermetabolic adenopathy is found in 9 patients and visceral involvement in one.Conclusions:Although the study population is small our findings suggests that 18F-FDG PET-CT can detect cutaneous and extracutaneous lesions in MF and may guide biopsies especially in patients with risk of secondary LN involvement.

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Utility of FDG-PET for Staging in a Case of Mycosis Fungoides

Cited by 6 publications

References 8 publications

Computed tomography scanning in mycosis fungoides: optimizing the balance between benefit and harm

Computed tomography scanning in mycosis fungoides: optimizing the balance between benefit and harm

Mycosis fungoides staged by 18F-flurodeoxyglucose positron emission tomography/computed tomography

The role of fluorine-18 fluorodeoxyglucose positron emission tomography in patients with mycosis fungoides

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