Utility of fine‐needle aspiration and core biopsy with touch preparation in the diagnosis of renal lesions

Abstract

BACKGROUND: Cytologic evaluation by fine-needle aspiration (FNA) and core biopsy (CB) with touch preparation (TP) is used in the diagnosis of renal lesions. METHODS: Consecutive image-guided FNA and CB, with or without TP, of renal lesions were reviewed. The cytology diagnoses were correlated with the radiology, surgical specimens, and clinical course.

Renal Mass Biopsy in the Era of Surgical Alternatives

“…Scanga and Maygarden, in a more recent study of 154 renal mass biopsy procedures, found slightly better results, with satisfactory specimen adequacy in 86 % of FNAs; core biopsies yielded satisfactory specimens in 94 % of cases [36]. Their results corroborate those of a previous study in which a higher rate of inadequate sampling was found in FNAs (11 %) versus core biopsy (3 %) [37].…”

“…Core biopsy gives more specific information than FNA for histologic tumor classification and grading [36]. In a study of 351 renal masses where both FNA and core biopsy samples were obtained, 21.6 % of the FNAs were diagnostic when the core biopsy was non-diagnostic [39].…”

Small renal masses in the era of personalized medicine: Tumor heterogeneity, growth kinetics, and risk of metastasis

“…Several studies have been performed by means of fluorescence in situ hybridization, and one field of research is aimed at defining which set of alterations can be held as "typical" of specific tumor subtypes. Anyway, this procedure is still investigational [16,[18][19][20][21].…”

Ancillary studies in fine needle aspiration of the kidney

“…Although FNA is both accurate and sufficient for diagnosing most common RCCs, most of the unusual RCCs require additional tissue for testing, meaning that the use of cell blocks and core needle biopsies are likely to become more critical, primarily to ensure adequate tissue for testing …”