Utility of fine needle aspiration in diagnosis of intraoral minor salivary gland tumors

Singh, Meeta; Sagar, Nishant; Yadav, Shobha; Aggarwal, Radhika; Mandal, Shramana; Khurana, Nita; Jain, Shyama; Meher, Ravi

doi:10.4103/joc.joc_62_19

Cited by 4 publications

(7 citation statements)

References 21 publications

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“…These included nine SRs, 8-16 two RCTs, 17,18 and 25 phase II, 19-43 28 prospective, 44-71 and 229 retrospective studies. 5,72-299 Identified trials focused on preoperative evaluations, surgical diagnostic and therapeutic procedures, radiotherapy techniques, and systemic therapy in SGM. The primary outcomes reported in studies on therapeutic interventions included overall survival (OS), progression-free survival (PFS), relapse-free survival, failure-free survival (FFS), disease-free survival (DFS) as well as distant FFS or control rate, locoregional FFS or control rate, and quality of life.…”

Section: Resultsmentioning

confidence: 99%

Management of Salivary Gland Malignancy: ASCO Guideline

Geiger

Ismaila

Beadle

et al. 2021

JCO

226

239

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PURPOSE To provide evidence-based recommendations for practicing physicians and other healthcare providers on the management of salivary gland malignancy. METHODS ASCO convened an Expert Panel of medical oncology, surgical oncology, radiation oncology, neuroradiology, pathology, and patient advocacy experts to conduct a literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective comparative observational studies published from 2000 through 2020. Outcomes of interest included survival, diagnostic accuracy, disease recurrence, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. RESULTS The literature search identified 293 relevant studies to inform the evidence base for this guideline. Six main clinical questions were addressed, which included subquestions on preoperative evaluations, surgical diagnostic and therapeutic procedures, appropriate radiotherapy techniques, the role of systemic therapy, and follow-up evaluations. RECOMMENDATIONS When possible, evidence-based recommendations were developed to address the diagnosis and appropriate preoperative evaluations for patients with a salivary gland malignancy, therapeutic procedures, and appropriate treatment options in various salivary gland histologies. Additional information is available at www.asco.org/head-neck-cancer-guidelines .

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Section: Resultsmentioning

confidence: 99%

Management of Salivary Gland Malignancy: ASCO Guideline

Geiger

Ismaila

Beadle

et al. 2021

JCO

226

239

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“…Já as glândulas salivares menores, segundo Sagar et al 23 em uma amostra de 64 espécimes, estima-se que o local mais comum de ocorrência é o palato duro (44%), seguido de palato mole (23%), assoalho da boca (12%), lábios (11%), mucosa bucal (5%) e língua (5%).…”

Section: Resultsunclassified

“…Ademais, constatou-se que o adenoma pleomórfico é o tumor mais recorrente, acometendo, dentre as glândulas salivares maiores, a parótida esquerda, e dentre as glândulas salivares menores, o palato duro. Estes dados também foram registrados por outros estudos [22][23]27 .…”

Section: Resultsunclassified

Perfil Clínico e Histopatológico das Neoplasias Benignas das Glândulas Salivares em Pacientes Diagnosticados em Serviço de Referência do Estado do Amazonas

et al. 2023

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Introdução: As neoplasias de glândulas de salivares representam algumas das principais causas de acometimento do aparelho estomatognático, sendo caracterizadas por lesões exclusivas da região oral, encontradas na forma de Tumores. Os tumores são lesões pouco frequentes, que dependendo do comportamento biológico variam desde lesões benignas a malignas, acometendo glândulas salivares maiores e menores. Objetivo: Traçar o perfil clínico e histopatológicos das neoplasias benignas de glândulas salivares diagnosticados em um serviço de referência no Estado do Amazonas num período de 15 anos. Materiais e métodos: Utilizou-se como população do estudo laudos de pacientes biopsiados, tendo como auxílio para coleta de dados fichas de registros elaboradas, que foram usadas para realização da tabulação e análise de dados. Resultados: A amostra foi composta por 35 pacientes diagnosticados com neoplasia benigna de glândula salivar. A glândula parótida e a região de palato duro foram os sítios mais predispostos e a lesão benigna mais prevalente foi o adenoma pleomórfico, principalmente em mulheres, na terceira década de vida. Conclusão: A variedade microscópica demonstra a diversidade histopatológica dessas lesões e são importantes para o conhecimento das neoplasias de glândula salivar na população local, além de servir de base para elaboração da hipótese diagnóstica em casos de suspeita de tumores benignos, auxiliando no manejo clínico, tratamento e prognóstico do paciente.

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“…Majority of intraoral minor SG tumours are malignant in contrast to major SG tumours where benign tumours outnumber the malignant ones [4]. While some studies documents mucoepidermoid carcinoma (MEC) as the most common malignant tumour of minor SGs, other studies documents adenoid cystic carcinoma (ADCC) or pleomorphic adenoma (PA) as the most common tumour [5][6][7][8][9][10]. This difference in frequency of these histological types may be attributed to the differences in geographic location, race and varied clinical presentation.…”

Section: Introductionmentioning

confidence: 99%

“…However, the papillary architecture of DP can help to distinguish it from MEC.d. Mucoepidermoid carcinoma (MEC)-It is the most common malignancy of intraoral SGs in young adults and children[7][8][9]. Palate is the most common site of occurrence.…”

mentioning

confidence: 99%

Cytopathology of Intraoral Salivary Gland Tumours and Tumour-Like Lesions: Diagnostic Challenges and Pitfalls

Chaurasia¹,

Kapoor²

2022

Oral Cancer - Current Concepts and Future Perspectives

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Fine needle aspiration cytology is an important diagnostic tool in cytopathology. There are many challenges and pitfalls encountered in intraoral salivary gland cytopathology as tumours of these glands show morphological diversity and overlapping features. There are often variable solid-cystic components, metaplastic or necrotic changes, fibrosis, hyalinisation and haemorrhage accounting for heterogeneity of these tumours. The tumour profile of intraoral salivary gland is quite different from the major salivary glands and needs special attention. A low-grade malignant tumour may sometimes mimic a benign neoplasm or a non-neoplastic lesion resulting in a false negative diagnosis. Moreover, misinterpretation and failure to recognize subtle morphological and architectural patterns of cells also pose diagnostic challenges. In this chapter, we intend to highlight the key cytopathological features of intraoral salivary gland tumours and tumour-like lesions with emphasis to overcome diagnostic challenges and pitfalls to avoid misdiagnosis which will aid in planning further management and treatment.

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Utility of fine needle aspiration in diagnosis of intraoral minor salivary gland tumors

Cited by 4 publications

References 21 publications

Management of Salivary Gland Malignancy: ASCO Guideline

Management of Salivary Gland Malignancy: ASCO Guideline

Perfil Clínico e Histopatológico das Neoplasias Benignas das Glândulas Salivares em Pacientes Diagnosticados em Serviço de Referência do Estado do Amazonas

Cytopathology of Intraoral Salivary Gland Tumours and Tumour-Like Lesions: Diagnostic Challenges and Pitfalls

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