2000
DOI: 10.1016/s0002-9610(00)00381-0
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Utility of fluorine-18-fluorodeoxyglucose positron emission tomography in differentiated thyroid carcinoma with negative radioiodine scans and elevated serum thyroglobulin levels

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Cited by 71 publications
(20 citation statements)
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“…Patients who at the 6-to 12-month follow-up have detectable rhTSH-stimulated Tg levels and abnormalities on other evaluation methods or rhTSH-stimulated Tg above the institutional cut-off also should receive such management. If the posttherapy WBS does not show any uptake, other imaging modalities may be employed: spiral computed tomography of the neck and chest, bone scintigraphy and [ 18 F]fluorodeoxyglucose positron emission tomography (FDG-PET) (33). FDG-PET may be more sensitive when performed following rhTSH stimulation (43).…”
Section: Subsequent Follow-up and Managementmentioning
confidence: 99%
“…Patients who at the 6-to 12-month follow-up have detectable rhTSH-stimulated Tg levels and abnormalities on other evaluation methods or rhTSH-stimulated Tg above the institutional cut-off also should receive such management. If the posttherapy WBS does not show any uptake, other imaging modalities may be employed: spiral computed tomography of the neck and chest, bone scintigraphy and [ 18 F]fluorodeoxyglucose positron emission tomography (FDG-PET) (33). FDG-PET may be more sensitive when performed following rhTSH stimulation (43).…”
Section: Subsequent Follow-up and Managementmentioning
confidence: 99%
“…Early detection of DTC relapse in these patients significantly increases the possibility of an effective treatment, especially in a case of local recurrence or single metastases amendable for surgery. In a patient with elevated serum Tg level, negative WBS and normal results of imaging studies fluorodeoxyglucose-positron emission tomography (FDG-PET) may be considered (6,7,8). It is in fact an examination dedicated for the diagnostics of other types of cancer that, in contrary to DTC, show a high dynamics and rapid cell divisions.…”
Section: Introductionmentioning
confidence: 99%
“…The 10-y survival rate of DTC is .80% because of treatments such as total thyroidectomy and ablation of remnants with radioiodine (13). However, metastases of thyroid carcinoma develop in 7%-23% of patients; the distant metastases occur commonly in the lungs, bones, and brain, and bones are the second common site of metastases from thyroid carcinoma (14).Several earlier reports showed that 18 F-FDG PET is highly sensitive in detecting DTC and is particularly useful for the evaluation of patients with negative radioactive iodine scintigraphy and elevated thyroglobulin levels (15)(16)(17)(18)(19)(20). For the detection of bone metastases of thyroid…”
mentioning
confidence: 99%
“…Several earlier reports showed that 18 F-FDG PET is highly sensitive in detecting DTC and is particularly useful for the evaluation of patients with negative radioactive iodine scintigraphy and elevated thyroglobulin levels (15)(16)(17)(18)(19)(20). For the detection of bone metastases of thyroid…”
mentioning
confidence: 99%