Utility of Pleural Fluid Analysis in Predicting Tube Thoracostomy/Decortication in Parapneumonic Effusions

Pleural-fluid myeloperoxidase in complicated and noncomplicated parapneumonic pleural effusions

“…Significant pleural complications still occur when using classical criteria to indicate pleural drainage, i.e.the presence of purulent pleural fluid, microorganisms on Gram-stain and/or positive culture andpleural pHv7.20 and/or pleural glucosev40 mg?100 mL -1 in the context of a clinical and radiological process [17,18]. There are three situations in which the usefulness of pH is subject to controversy: 1) in cases where pH is between 7-7.2, there is no consensus as to the ideal approach to take and opinions range from the use of conservative treatment, i.e.…”

“…Measurements of pH are, however, dependant on the mode of sample carriage and delay in measurement [16]. A fluid glucose value v40 mg?dL -1 or a located hydogenase (LDH) value w1,000 IU?L -1 has also been used in the early diagnosis of complicated PPE [3], although the development of pleural thickening in the evolution of complicated PPE is not unusual [17,18]. In view of the persistence of local complications a prospective study, to evaluate whether pleural-fluid MPO concentration might be useful for early differentiation between complicated and noncomplicated PPE, was performed.…”

Fatores preditivos para drenagem de derrames pleurais parapneumônicos em crianças

“…Os achados relativos à dosagem da glicose mostraram sensibilidade elevada na predição de drenagem, embora tenha sido inferior ao que é descrito na literatura (17) . Quanto à especificidade, esta mostrou-se superior à encontrada por Poe et al (17) .…”

“…Quanto à especificidade, esta mostrou-se superior à encontrada por Poe et al (17) . O risco relativo foi elevado ao analisar o conjunto de pacientes e ao excluir aqueles com lí-quido purulento à toracocentese.…”

Resistance to Co-Amoxiclav (Augmentin) in Community-Acquired and Nosocomial Pleural Infections

“…PF pH and glucose were higher, though, false positive of PF culture might account for misdiagnosis. However, previous studies reported that some patients with PF pH >7.2 do need tube thoracostomy or decortication [26]. Moreover, every subject had clinical signs of overt pleural infection in our series.…”