Utility of Ranson score, computed tomography severity index and CRP criteria in risk stratification on the day of hospital admission in patients with acute pancreatitis: A cross-sectional analysis

Duru, Hüseyin

doi:10.14744/tjtes.2022.33332

Cited by 2 publications

(5 citation statements)

References 40 publications

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Section: Discussionmentioning

confidence: 99%

“…Our study is significant as it is the first to evaluate SAL-β levels in patients with AP. [8][9][10][11][12] While most cases of AP follow a mild course, severe forms demand increased attention due to their high morbidity and mortality. Several single and multiparametric scoring systems have been defined to assess the severity of the disease by, incorporating laboratory parameters and physiological and radiological assessments.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, since these parameters used in daily practice are increased in many diseases, their use may not be safe in predicting severe pancreatitis, just like CRP, as seen in our results. [12,[33][34][35] The main limitation of our study was its small sample size. No statistically significant differences were found between the mild and moderate pancreatitis groups.…”

Section: Discussionmentioning

confidence: 99%

“…Our study is significant as it is the first to evaluate SAL-β levels in patients with AP. [ 8 – 12 ]…”

Section: Discussionmentioning

confidence: 99%

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Relationship between salusin beta levels and the severity of acute pancreatitis in patients

Albayrak,

Guneyin,

Celik

2024

Medicine

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Background: This study aimed to evaluate the significance of serum salusin beta (SAL-β) levels in predicting the severity of acute pancreatitis (AP) in patients diagnosed with this condition and to assess its relationship with disease and prognosis. Methods: Sixty-four patients between 18 and 100 years of age diagnosed with AP, were included in the study. Patients were categorized into 3 groups based on the Revised Atlanta Classification: mild, moderate, and severe AP. Eighteen healthy adults were included as the control group. Sex, age, height, weight, presence of additional diseases, laboratory results, imaging findings, levels of white blood cells, neutrophil-lymphocyte ratio, mean platelet volume, amylase, lipase, sensitive C-reactive protein, sedimentation, and serum SAL-β were measured and recorded. SAL-β levels were reevaluated on the third day of hospitalization. Results: The average age of the patients included in the study was 62.66 ± 17.67. Gallstones were present in 64.1% of the patients. The difference in the SAL-β averages on the 1st and 3rd days was statistically significant (P < .05). On the first day, the SAL-β averages of those with severe Atlanta scores were higher than those with mild and moderate Atlanta severity. Similarly, on the third day, the SAL-β averages of those with severe Atlanta scores were higher than those with mild and moderate Atlanta severity. According to receiver operating characteristic analysis using the Youden index, the cutoff value for SAL-β for severe pancreatitis was 178.8 pg/mL on the 1st day and 207.5 pg/mL on the 3rd day. Conclusion: SAL-β can be used to detect and monitor severe pancreatitis. Further extensive clinical studies with larger case series are needed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Our study is significant as it is the first to evaluate SAL-β levels in patients with AP. [ 8 – 12 ]…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Relationship between salusin beta levels and the severity of acute pancreatitis in patients

Albayrak,

Guneyin,

Celik

2024

Medicine

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“…On the other hand, they cannot be displayed graphically. [9,10] Herein, more attention was paid to the Ranson score as it is the most widely used and has maintained its clinical effectiveness for years. In clinical practice, the data demonstrated that the imaging findings of the pancreas on an early computerized tomography (CT) scan could only reflect the severity at the time of admission, but could not predict the prognosis of HTG-AP.…”

Section: The Present Study Was Supported By the Foundation Of Health ...mentioning

confidence: 99%

Prediction of severe hypertriglyceridemia-associated acute pancreatitis using a nomogram based on CT findings and blood biomarkers

Dong,

Shen,

Wang

et al. 2024

Medicine

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Hypertriglyceridemia is a common cause of acute pancreatitis (AP). Fatty liver, a manifestation of metabolic syndrome, is related to the severity of AP. The present study aimed to construct an accurate predictive model for severe AP (SAP) by combining the fatty liver infiltration on a computerized tomography (CT) scan with a series of blood biomarkers in patients with hypertriglyceridemia-associated AP (HTG-AP). A total of 213 patients diagnosed with HTG-AP were included in the present retrospective study. Clinical information and imageological findings were retrospectively analyzed. The model was constructed from independent risk factors using univariate analysis, the least absolute shrinkage and selection operator method. Subsequently, the data from the training group of 111 patients with HTG-AP was analyzed using logistic regression analysis. The efficacy of the model was verified using an external validation group of 102 patients through the receiver operating characteristic curve (ROC). Independent predictors, including serum calcium, C-reactive protein, lactate dehydrogenase and liver-to-spleen CT attenuation ratio (L/S ratio), were incorporated into the nomogram model for SAP in HTG-AP. The model achieved a sensitivity of 91.3% and a specificity of 88.6% in the training group. Compared with the Ranson model, the established nomogram model exhibited a better discriminative ability in the training group [area under the curve (AUC): 0.957] and external validation group (AUC: 0.930), as well as better calibration and clinical benefits. The present study demonstrates that the constructed nomogram based on CT findings and blood biomarkers is useful for the accurate prediction of SAP in HTG-AP.

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Utility of Ranson score, computed tomography severity index and CRP criteria in risk stratification on the day of hospital admission in patients with acute pancreatitis: A cross-sectional analysis

Cited by 2 publications

References 40 publications

Relationship between salusin beta levels and the severity of acute pancreatitis in patients

Relationship between salusin beta levels and the severity of acute pancreatitis in patients

Prediction of severe hypertriglyceridemia-associated acute pancreatitis using a nomogram based on CT findings and blood biomarkers

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