2013
DOI: 10.1016/j.urology.2013.04.026
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Utility of Screening Ultrasound After First Febrile UTI Among Patients With Clinically Significant Vesicoureteral Reflux

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Cited by 60 publications
(51 citation statements)
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“…This means that 50% of the 38 typical UTIs, with no signs of abnormalities by RBUS, would have a high-grade reflux. This finding agreed well with the recent findings by Massanyi et al (2013); according to their study, one hundred fifty-eight kidneys had evidence of VUR on VCUG, and initial RBUS demonstrated abnormality only in 25 (sensitivity 0.17); forty-five kidneys had high-grade VUR and RBUS revealed abnormality only in 16 (sensitivity 0.36). Based on these, they concluded that RBUS has poor sensitivity and negative predictive value for detecting highgrade VUR in patients less than 2 years who present with a febrile UTI, i.e., a significant number of patients who were diagnosed with high-grade VUR had a negative screening RBUS.…”
Section: Discussionsupporting
confidence: 91%
“…This means that 50% of the 38 typical UTIs, with no signs of abnormalities by RBUS, would have a high-grade reflux. This finding agreed well with the recent findings by Massanyi et al (2013); according to their study, one hundred fifty-eight kidneys had evidence of VUR on VCUG, and initial RBUS demonstrated abnormality only in 25 (sensitivity 0.17); forty-five kidneys had high-grade VUR and RBUS revealed abnormality only in 16 (sensitivity 0.36). Based on these, they concluded that RBUS has poor sensitivity and negative predictive value for detecting highgrade VUR in patients less than 2 years who present with a febrile UTI, i.e., a significant number of patients who were diagnosed with high-grade VUR had a negative screening RBUS.…”
Section: Discussionsupporting
confidence: 91%
“…3,[13][14][15][16] El abordaje más selectivo propuesto en 2011, si bien reduce el número de CUGM negativas, 6 también generó preocupación en relación con la posibilidad de que se retrasara el diagnóstico de patología relevante, 7 especialmente sabiendo que la ecografía es un método con baja sensibilidad y especificidad para detectar RVU. 8,17,18 Apoyando esto, K. D. Suson y R. Mathews encontraron que el 62% de los pacientes de entre 2 y 24 meses con ecografía renal normal luego de la primera ITU, sin considerar si había sido atípica, presentaba RVU ≥ grado III y que el 17% también tenía escaras renales. 7 En nuestra serie, se detectó patología significativa luego de la primera ITU en más de un tercio (37,5%) de los casos, lo que permitió identificar precozmente a un grupo de pacientes pasible de intervenciones terapéuticas.…”
Section: Discussionunclassified
“…4 • Ecografía renal y de vía urinaria normal: ambos riñones de forma, tamaño y ecoestructura normal, ausencia de hidronefrosis y vejiga normal. 8 • RVU: pasaje retrógrado de orina de la vejiga hacia los uréteres diagnosticado por CUGM y clasificado en cinco grados según la Clasificación Internacional de RVU. • C e n t e l l o g r a m a r e n a l c o n á c i d o dimercaptosuccínico (dimercaptosuccinic acid; DMSA, por sus siglas en inglés) patológico: presencia de escaras (áreas de hipocaptación focalizada) o función diferencial mayor de 10% entre ambos riñones, luego de un intervalo mínimo de 6 meses desde la última ITU.…”
Section: Métodosunclassified
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“…Moreover, recent studies have shown the limited value of US for children after the first UTI because of its poor ability in detecting VUR and RS, as well as its lack of impact on subsequent management or care [9][10][11][12][13][14][15]. By contrast, other authors claim that US can accurately detect obstructive uropathy, kidney size, renal abscess, and ureterocele in hospitalized children, thereby directly influencing subsequent management based primarily on US examination and suggesting that US should be carried out routinely in children with the first UTI [16][17][18][19][20].…”
Section: Introductionmentioning
confidence: 99%