Utility of TEMPS-A in differentiation between major depressive disorder, bipolar I disorder, and bipolar II disorder

Morishita, Chihiro; Kameyama, Rie; Toda, Hiroyuki; Masuya, Jiro; Ichiki, Masahiko; Kusumi, Ichiro; Inoue, Takeshi

doi:10.1371/journal.pone.0232459

Cited by 20 publications

(28 citation statements)

References 28 publications

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“…Secondly, we did not compare affective temperaments between BD-II and BD-I patients, because of the relatively small sample size, whereas our recent research using the full-length version of TEMPS-A indicated that hyperthymic temperament may be useful to differentiate BD-I patients from BD-II patients. 25 A large-scale study should be performed to verify whether each affective temperament on the shortened version of TEMPS-A is a differentiating feature between BD-II and BD-I.…”

Section: Discussionmentioning

confidence: 99%

“…Specifically, anxious and cyclothymic temperaments were identified as factors differentiating patients with MDD and BD from healthy controls, 11,12 and were also found to be factors that can identify patients with BD among those with mood disorders. 25 The above studies used the full-length version of TEMPS-A, which consists of 110 items. However, the full-length version of TEMPS-A is thought to be difficult to complete for patients with severe depressive and manic symptoms, because much time and effort are needed.…”

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confidence: 99%

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TEMPS‐A (short version) plays a supplementary role in the differential diagnosis between major depressive disorder and bipolar disorder

Morishita

Kameyama

Toda

et al. 2021

Psychiatry Clin Neurosci

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Aim: Early differential diagnosis between patients with major depressive disorder (MDD) and bipolar disorder (BD), and subsequently providing appropriate treatments are essential. There has been increased interest regarding the association between affective temperaments and mood disorder diagnosis. Our aim was to analyze the diagnostic validity of affective temperaments assessed by the short version of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version (TEMPS-A), in mood disorder patients.Methods: Inpatients with MDD (n = 146) or BD (n = 128) completed the short version of TEMPS-A, and their depressive and manic symptom severities were evaluated. Data of MDD and BD patients were compared by univariable and multivariable analyses.Results: Of the five affective temperament dimensions, substantially higher hyperthymic, irritable, and cyclothymic temperament scores were found in BD patients than in MDD patients. Using a multivariable logistic regression model built using the severities of depressed and manic conditions, and the five affective temperament subscale scores as independent variables, we identified two factors statistically associated with BD diagnosis (anxious temperament and cyclothymic temperament). The recommended cutoff point for the 12 items evaluating cyclothymic temperament to differentiate BD from MDD was 8 or more 'True' items (sensitivity: 35.9%, specificity: 87.7%).Limitations: Our design was cross-sectional, and therefore, there was a possibility of longitudinal diagnostic conversion of patients from MDD to BD. Conclusion:Cyclothymic and anxious temperaments on the short version of TEMPS-A, identified as diagnostic differentiating factors between MDD and BD, may play supplementary roles in the early identification of BD.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

TEMPS‐A (short version) plays a supplementary role in the differential diagnosis between major depressive disorder and bipolar disorder

Morishita

Kameyama

Toda

et al. 2021

Psychiatry Clin Neurosci

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“…Recent literature shows that TEMPS-A as a tool has been found useful in determining affective disorders and in other conditions like insomnia or pain syndrome. 29–31 The evaluation of affective temperament seems to determine which of the infertile women are more prone to the development of depression and anxiety. 32 Moreover, recent research in a group of gestational diabetes patients showed promising data regarding the association between affective temperament and the development of gestational diabetes, as well as disturbances in glycemic metabolism in this group of patients.…”

Section: Introductionmentioning

confidence: 99%

Affective Temperament and Glycemic Control – The Psychological Aspect of Obesity and Diabetes Mellitus

Lesiewska¹,

Kamińska²,

Junik³

et al. 2021

DMSO

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Purpose Affective temperament shows innate predisposition to affective disorders and has been studied in patients with type 2 diabetes mellitus (T2DM) and obesity. Studies describing connections between depressive disorders, obesity and T2DM, show a bidirectional way in which these disorders affect each other. Given that obesity, depression, and T2DM are still growing health problems of our times, the improvement of therapeutic strategies is required. The aim of our study was to evaluate affective temperament in obese individuals with T2DM and pre-diabetes and to investigate the correlations between affective temperaments and glycemic control. Materials and Methods The study enrolled 185 obese individuals (146 females; 39 males) who were diagnosed with pre-diabetes, diabetes or without any carbohydrate disorder. For affective temperament evaluation, Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire (TEMPS-A) was utilized; for glycemic control, the assessment of hemoglobin A1c (HbA1c) was performed. Results We did not observe any significant differences of affective temperament between studied groups. In the group of patients with diabetes, depressive, cyclothymic and anxious temperaments positively correlated with HbA1c values indicating worse glycemic control. Inversly, hyperthymic dimension showed negative correlation with HbA1c values. Conclusion Affective temperaments may affect glycemic control in obese individuals with carbohydrate disorders. Individuals with stronger expression of cyclothymic, depressive and anxious temperaments may need more medical aid for better self-management. Hence, TEMPS-A is an easy and useful tool which may significantly improve the compliance in obese patients with carbohydrate disorders.

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“…Several studies have focused on temperament assessments in individuals diagnosed with MDD [15][16][17] or with BD specifically [18][19][20][21][22][23][24], or have considered mood disorders together using TCI [25,26] or TEMPS [1,[27][28][29][30]. Such studies have revealed differences between mood disorder patients and controls, including unaffected family members, with suggestive differences between BD and MDD patients and possibly between BD-1 and BD-2 patients based on ratings of cyclothymic, hyperthymic, and irritable temperaments, in particular, as well as ratings of harm-avoidance [1,[31][32][33].…”

Section: Introductionmentioning

confidence: 99%

Relationships of affective temperament ratings to diagnosis and morbidity measures in major affective disorders

Miola

Baldessarini

Pinna³

et al. 2021

Eur. Psychiatr.

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Background. Ratings of affective temperament types show promise in helping to differentiate diagnostic groups among major affective disorders as well as to predict associations with important aspects of morbidity including suicidal risk. Methods. The Temperament Evaluation of Memphis, Pisa, Paris, and San Diego auto-rating (TEMPS-A) questionnaire was completed by 858 unselected, consecutive, consenting adults diagnosed with a DSM-5 major affective disorder (173 bipolar-1 [BD-1]), 250 BD-2, 435 major depressive disorder [MDD]) to score for anxious (anx), cyclothymic (cyc), dysthymic (dys), hyperthymic (hyp), and irritable (irr) affective temperaments. We tested their associations with diagnosis and selected clinical factors, including diagnosis, depression scores, suicidal ideation or acts, substance abuse, episodes/year, and %-time ill. Results. Scores for cyc ranked: BD-2 > BD-1 > MDD; anx ranked: MDD > BD-2 > BD-1; irr was greater in BD than MDD; dys was greater in MDD than BD; hyp did not differ by diagnosis. We confirmed associations of suicidal risk with higher scores of all temperament types except lower hyp scores. Higher cyc and irr scores and lower anx scores were associated with substance abuse. Several scores were higher with measures of greater affective morbidity: cyc with current depression, episodes/year, and %-time ill; irr with more episodes and depressions/year and greater %-time manic. Some of these associations were selective for BD or MDD. Conclusions. The findings indicate that TEMPS-A ratings of affective temperament types can contribute to differential diagnoses and predict types and amounts of affective morbidity, as well as detecting suicidal risks.

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Utility of TEMPS-A in differentiation between major depressive disorder, bipolar I disorder, and bipolar II disorder

Cited by 20 publications

References 28 publications

TEMPS‐A (short version) plays a supplementary role in the differential diagnosis between major depressive disorder and bipolar disorder

TEMPS‐A (short version) plays a supplementary role in the differential diagnosis between major depressive disorder and bipolar disorder

Affective Temperament and Glycemic Control – The Psychological Aspect of Obesity and Diabetes Mellitus

Relationships of affective temperament ratings to diagnosis and morbidity measures in major affective disorders

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