Utility of vertebral biopsy before vertebroplasty in patients with diagnosis of vertebral compression fracture

Sozzi, Carlo; Trentadue, Mirko; Nicolì, Lisa; Tavani, Federica; Piovan, E.

doi:10.1007/s11547-021-01353-9

Cited by 10 publications

(4 citation statements)

References 13 publications

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“…Osteoporosis is the most common cause of vertebral compression fracture ( 1 ) . Even when such fractures are treated aggressively, morbidity and mortality remain high ( 2 ) , with reduced life expectancy, impaired quality of life ( 3 - 5 ) , and estimated costs of approximately €75 billion projected for the year 2050 in Europe ( 3 , 6 ) .…”

Section: Discussionmentioning

confidence: 99%

“…Despite the existence of a direct correlation between the BMD T-score and fracture risk, it is estimated that half of postmenopausal women who suffer a fracture caused by low-energy trauma have a BMD that is above the World Health Organization threshold for the diagnosis of osteoporosis, which is defined as a T-score equal to or greater than -2.5 ( 1 , 15 ) . The BMD alone does not reflect bone quality, which also significantly affects bone strength and fracture risk ( 3 , 15 - 17 ) .…”

Section: Discussionmentioning

confidence: 99%

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Magnetic resonance imaging at 3.0-T in postmenopausal osteoporosis: a prospective study and review of the literature

Trentadue¹,

Sozzi

Idolazzi

et al. 2022

Radiol Bras

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Objective: To promote advanced research using magnetic resonance imaging (MRI) in the diagnosis of and screening for osteoporosis by looking for correlations among the T-scores measured by dual-energy X-ray absorptiometry (DEXA), the apparent diffusion coefficient (ADC) values on diffusion-weighted imaging (DWI), and the T1-weighted signal intensity values. Materials and Methods: This was a prospective study of postmenopausal women with no contraindications to MRI and no history of cancer who underwent DEXA within 30 days before or after the MRI examination. A 3.0-T scanner was used in order to acquire sagittal sequences targeting the lumbar spine. Results: Thirteen women underwent DEXA and MRI. In two cases, the MRI was discontinued early. Therefore, the final sample comprised 11 patients. The ADC values and T1-weighted signal intensity were found to be higher in patients with osteoporosis. However, among the patients > 60 years of age with osteoporosis, ADC values were lower and T1-weighted signal intensity was even higher. Conclusion: It is unlikely that MRI will soon replace DEXA for the diagnostic workup of osteoporosis. Although DWI and ADC mapping are useful for understanding the pathophysiology of osteoporosis, we believe that T1-weighted sequences are more sensitive than is DWI as a means of performing a qualitative analysis of vertebral alterations.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging at 3.0-T in postmenopausal osteoporosis: a prospective study and review of the literature

Trentadue¹,

Sozzi

Idolazzi

et al. 2022

Radiol Bras

Self Cite

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“…Medical images captured in the form of X-rays, CT and MRI images allows VCF diagnosis [11]. As spinal X-ray images consists of lateral and anteroposterior exposures of vertebrae, it acts as a basic diagnostic modality in case of VCFs as it promotes imaging modality accessibility speed over clinical practices [12][13].…”

Section: ░ 1 Introductionmentioning

confidence: 99%

Vertebra Segmentation Based Vertebral Compression Fracture Determination from Reconstructed Spine X-Ray Images

Gadu,

Potala

2023

IJEER

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The vertebral compression fracture represents the vertebral body deformity appeared over lateral spine imageries. In order to evaluate the vertebral compression fracture (VCF), the vertebral compression ratio (VCR) has to be accurately measured. In most of the existing vertebral segmentation approaches, degraded accuracy, increased possibilities of error and time complexity are found to be the major drawbacks. Hence to conquer these issues and to enhance the overall segmentation performance, rapid automated vertebral segmentation approach is proposed for evaluating the VCR. Initially the reconstructed spine X-ray images are collected and directed over the Hybrid UDA Net architecture from this model, the features are extracted using encoder section of U-net architecture through the adoption of channel attention layer (CaL) and hybrid attention dilated Quantum convolutional layer (HaDQcL). The segmental outcomes are accomplished through the decoder section of U-Net. Based on the extracted features given as the input, exact segmentation of spinal images is attained using Twin attention mechanism called Gated-decoder attention module (GDAM). Through GDAM, the segmented spine X-ray images are obtained with effective results through the fusion of spatial and channel features in decoder attention module. The losses in the neural network are optimized using Amended pelican optimization algorithm (APoA). The diverse stages of VCF are finally analysed through VCR evaluation. The overall accuracy of 98.41%, F1 score of 96.75% and specificity of 99% is obtained by the proposed model whereas the performance is analysed using PYTHON. On comparison of proposed and existing models, the proposed model through segmentation and VCF diagnosis are highly superior.

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“…Using a puncture needle to penetrate the vertebral body from the pedicle and inject bone cement can enhance the strength and structural stability of the vertebral body and reduce bone pain. 1 , 2 PVP can reduce the risk of complications such as lower extremity deep venous thrombosis and prolapse pneumonia caused by long-term bed rest with conventional conservative treatment. 3 However, since the degree of osteoporosis of patients varies, the clinical efficacy of different approaches of PVP is different.…”

Section: Introductionmentioning

confidence: 99%

Comparison of different approaches of percutaneous vertebroplasty in the treatment of osteoporotic spinal compression fractures and analysis of influencing factors of re-fracture

He²

2022

Pak J Med Sci

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Objective: To compare the functional and radiological outcome of different approaches of percutaneous vertebroplasty (PVP) in the treatment of osteoporotic vertebral compression fractures (OVCF), and to analyze the factors affecting postoperative re-fracture in patients with OVCF. Methods: Medical data of 76 patients with OVCF who underwent PVP in our hospital from January 2021 to December 2021 were analyzed retrospectively. Based on the different intraoperative approaches, patients were divided into Unilateral-group (n=36) and Bilateral-group (n=40). The perioperative indexes, clinical efficacy, and spinal nerve function of the two groups were compared. Logistic regression analysis was used to determine the risk factors of postoperative re-fracture in patients with OVCF. The functional outcome was assessed with Oswestry disability index (ODI), American Spinal Injury Association (ASIA) nerve function classification and pain with Visual analogue scale (VAS). The radiological outcome was assessed by noting change of anterior vertebral height and change of kyphosis Cobb angle. Results: The amount of intraoperative bleeding, the number of X-ray irradiation and the volume of injected bone cement in the Unilateral-group were lower, and the operation time was shorter than Bilateral-group (all P<0.05). One week after the operation, the anterior height of the vertebral body was higher, the Cobb angle of kyphosis was lower, the VAS score was higher, and the ASIA grade was lower in the Unilateral-group compared to the Bilateral-group (P<0.05). Logistic regression analysis showed that the age, bone mineral density, volume of bone cement injection and PD were risk factors of postoperative re-fracture in patients with OVCF. Conclusion: Unilateral PVP treatment of OVCF has the advantages of less intraoperative bleeding, less X-ray irradiation and shorter operation time. At the same time, bilateral PVP is associated with improved bone cement dispersion, and the effect of improving patients’ pain is better than that in the Unilateral PVP. Postoperative risk of re-fracture in OVCF patients correlated with age, bone mineral density, amount of bone cement injection and pedicle diameter. doi: https://doi.org/10.12669/pjms.39.1.7069 How to cite this: Bu D, He X. Comparison of different approaches of percutaneous vertebroplasty in the treatment of osteoporotic spinal compression fractures and analysis of influencing factors of re-fracture. Pak J Med Sci. 2023;39(1):---------. doi: https://doi.org/10.12669/pjms.39.1.7069 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Utility of vertebral biopsy before vertebroplasty in patients with diagnosis of vertebral compression fracture

Cited by 10 publications

References 13 publications

Magnetic resonance imaging at 3.0-T in postmenopausal osteoporosis: a prospective study and review of the literature

Magnetic resonance imaging at 3.0-T in postmenopausal osteoporosis: a prospective study and review of the literature

Vertebra Segmentation Based Vertebral Compression Fracture Determination from Reconstructed Spine X-Ray Images

Comparison of different approaches of percutaneous vertebroplasty in the treatment of osteoporotic spinal compression fractures and analysis of influencing factors of re-fracture

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