2023
DOI: 10.1093/jaoacint/qsad067
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Utilization of Chemometric-Aided UV Spectrophotometric Methods for Concurrent Assessment of Emtricitabine, Tenofovir Disoproxil Fumarate, Elvitegravir, and Cobicistat in Tablet Formulation

Abstract: Background Emtricitabine (ETC), Tenofovir disoproxil fumarate (TNF), Elvitegravir (EVG), and Cobicistat (CBS) are antiviral drugs used to treat human immunodeficiency virus (HIV) infections. Objective To develop chemometric-aided UV spectrophotometric methods for concurrent estimation of the aforementioned drugs used to treat HIV. This method can be used to reduce the modification of the calibration model by assessing the abs… Show more

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